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Three Parts of the Cell
Plasma Membrane
Cytoplasm
Nucleus
Cytoplasm
The gel-like substance of a cell exclusive of the nucleus and other organelles
Endoplasmic Reticulum (ER)
Network of tubules and vesicles in cytoplasm; two types: rough and smoothe
Lysosome
Membranous organelles containing various enzymes that can dissolve most cellular compounds; thus called digestive bags or suicide bags of cells
Microvillus
Brushlike border made up of epithelial cells found on each villus in the small intestine and other areas of the body; increases the surfae area (as for absorption of nutrients)
Mitochondrion
Organelle in which ATP generation occurs; aka the power house of the cell
Nucleolus
Intercellular structure critical to protein formation because it “programs” the formation of ribosomes in the nucleus
Nucleus
Spherical structur within a cell; a group of neuron cell bodies in the brain or spinal cord; center core of the atom, made up of protons and (sometimes) neutrons
Rough ER
Smooth ER
Plasma Membrane
Membrane that separates the contents of a cell from the tissue fluid; encloses the cytoplasm and forms the outer boundary the cell
Ribosome
Organelle in the cytoplasm of cells that synthesie proteins; aka protien factory
Hypertrophy (Changes in Growth of Individual Cells)
Increase in size of individual cells
Atrophy (Changes in Growth of Individual Cells)
Decrease of size of individual cells
Hyperplasia (Changes in Cell Reproduction)
Increase in cell reproduction
Anaplasia (Changes in Growth of Individual Cells)
Production of atypical, undifferentiated cells
DNA Replication
DNA molecules are somewhat unusual in that, the unlike most molecules in nature they can make identical copies of themselves.
Mitosis
The process of dividing the replicated genetic material. The DNA of the nucleus is an orderly way so that each resulting offspring cell has a complete identical set.
Cell Life Cycle
The proces of cell reproduction is one part of the cell’s life cycle.
Interphase
1st in the cell life phase: Cell growth. Replication od chromosomes. Cell not actively dividing. Most of the cell’s lifespan is spent in interphase.
Prophase
2nd of the cell life phase: The chromatin condenses into visible chromosomes. Chromatids become attached at the centromere. Spindle fibers appear. The nucleolus and nuclear envelope disappear.
Metaphase
3rd in the cell life cycle: Spindle fibers attach to each chromatid. Chromosomes align across the center of the cell.
Anaphase
4th in the cell life cycle: Centromeres break apart. Chromosomes move away from the center of the cell. The cleavage furrow appears
Telophase
5th in the cell life cycle: The nuclear envelope and both nuclear appear. The cytoplasm and organelles divide equally. The process of cell division is completed.
Transfer RNA (tRNA)
Molecules assist the process by bringing specific amino acids to the “dock” at each codon along with the mRNA. Codon = a series of thee nucleotide bases - a triplet - that acts as a code representing a sepcific amino acid.
Protein Synthesis
The process of transferring genetic information from the nucleus into the cytoplasm, where protein are actually produced, requires completion of two steps (transcription/ translation).
Transcription
The double stranded DNA molecule separates or unwinds, and a special type of RNA called messenger RNA
Translation
The process of “translating” the genetic code in the mRNA transcrip to synthesize a protein.
DNA Content
Genetic information totalling about 3 billion base pairs in perhaps 19,000 or so protein-coding genes.
Gene
Specific segment of base pairs in a chromosome
DNA
Chromosomes, which are composed largely of DNA contain the information needed to make all the proteins of the cells. The information allows a cell to live and function.
Function of genes
Genes copied from DNA are copied to RNA in transcription. The RNA transcripts are used in translation which code that determines the sequence of amino acids is translated to form a protein. The structure of the resulting protein determines the role of the protein in body structure and function- and the ultimately, their structure and function of the body.
Cholera
Bacterial infection that causes cell lining the intestines to leak
Cystic Fibrosis (CF)
An inherited condition that involves a variant of the gene that codes for chloride ion
Pino
Greek word meaning “drink”
Phagocytosis
Greek word meaning “to eat”
Ion Pumps
A complex membrane component called the ion pump makes possible a number of active transport mechanisms.
Active Transport
Uphilll movement of a substance through a living cell membrane
Down a hydrostatic pressure gradient
When two fluids have unequal hydrostatic pressure and are separated by a membrane, water and diffusible solutes or particles.
Filtration
The movement of water and solutes through a membrane as a result of pushing force that is greater on one side of the membrane than the other side.
Dialysis
Some solutes move across a selectively premable membranme by diffusion and other solutes don’t
Passive Transport
Movement from high to low concentration
Diffusion
Movement of particles through a membrane from an area of high concentration to an area of low concentration - that is, down the concentration gradient.
Osmosis
Passive movement of eater through a selectively premeable membrane in the presence of at least one non penetrating solute.
Filtration
Movement of water and small solute particles, but not larger particles, through a filtration membrane; movement occurs from area of high pressure to area of low pressure.
ATP
Energy required for active transport processes is obtained from ATP
Relationship of Cell Structure and Function
Every human cell performs certain functions. Some maintain the cell’s survival and others help maintain the body’s survival.
Chromosomes
During cell division, DNA molecules become tightly coiled. Then they look like short rodlike structures called chromosomes.
Chromatin granules
In the nucleus made of proteins around which are wound segments of the long, threadlike molecules called DNA (deoxyribonucleic acid).
Nucleus
Brain of the cell
Flagella
Single projection extending from the cell structure. Similar to Cilia but much longer. One EX is sperm bcause they got tails
Cilia
Extremely fine, hairlike extensions on the exposed or free surfaces of cells. EX: clears respiratory track
Microvilli
Small, fingerlike projections of the plasma membrane of some cells
Centrosome
Nonmembranous, dense region of cytoplasm near the nucleus of each cell. Serves as the microtubule organizing center of the cell.
Centrioles
Paired organelles found within the centrosome