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Desired FiO2 formula
= (current FiO2 x desired PaO2) / current PaO2
Desired RR formula
= (current RR x current PaCO2) / desired PaCO2
Desired Vt formula
= (current PaCO2 x current Vt) / desired PaCO2
Desired VA (alveolar ventilation) formula
= (Current VA × Current PaCO2) / Desired PaCO2
a high minute ventilation will result in a ____ PaCO2
low
a low minute ventilation will result in a ____ PaCO2
high
If PaO2 is too low what can you change
increase FiO2 and/or PEEP
if PaO2 is too high what can you change
decrease FiO2 first, then decrease PEEP if needed
Oxygenation changes are made by
FiO2 and PEEP
Ventilation changes are made by
RR and Vt
If PaCO2 too high what change can you make
increase RR or Vt (prefer RR first if volumes already lung-protective)
If PaCO2 too low what changes can you make
decrease RR or Vt
norm flow trigger setting
1-10L/min below base flow
flow triggering mechanism
continuous bias flow in circuit; pt’s insp effort reduces flow to trigger
flow triggering pros
faster response
more comfortable
gas continues to flow during exhalation
norm pressure trigger setting
-1 to -2 cmH2O
mechanism of pressure triggering
pt generates negative pressure; exhalation valve must close to sense change
pressure triggering risk
if set too negative (ex: -4 to -5 cmH2O), effort is excessive
what can make it too difficult for pt to trigger flow
if the difference set between base flow and flow trigger is too large
what can make it too difficult for pt to trigger pressure
if set more negative than -2 cmH2O
clinical cue of pt having difficulty triggering breathe
pt showing increased WOB, accessory muscle use, missed triggers
if vent is alarming what are the 3 steps you as an RT should do
step 1: go to pt - ensure they are being ventilated
step 2: if unsure or pt unstable, disconnect from vent and bag with 100% O2
step 3: then troubleshoot machine/circuit
pt problems that could result in vent alarming
bronchospasm
secretions
pneumothorax
decreased compliance
agitation
circuit/equipment problems that could result in vent alarming
disconnection
leak
kinked tubing
water in circuit
malfunctioning valve
pressure limit alarm setting
~10 cmH2O above PIP
low-pressure alarm setting
~5-10 cmH2O below PIP
what to inspect for leak check
around humidifier
connections
ETT cuff
water traps
COPD primary goal for vent management
reduce air trapping and WOB
COPD vent management strategy (Vt, rr, flow, PEEP)
Vt: 6-8mL/kg
rr: 8-16/min
Flow: >60 L/min (shorter insp time)
PEEP: low/modest; careful w/ auto-PEEP
COPD vent management targets (Pplat, PaO2, FiO2)
Pplat < 30cmH2O
PaO2 55-75 mmHg
FiO2 < 50%
high-yield risk for COPD on vent
dynamic hyperinflation/auto-PEEP
asthma primary goal for vent management
avoid air trapping and excessive pressures
asthma vent management strategy (mode, rr, Vt, I time, flow)
VC-CMV or PC-CMV
rr < 8 → long expiratory time for severe obstruction
Vt 6-8mL/kg
TI ≤ to 1 sec
flow 80-100 L/min
asthma vent management targets (CO2, pH)
premissive hypercapnia w/ pH ≥ to 7.2
risks for asthma pts on vent
air trapping, high peak/plateau pressure
neuromuscular weakness vent management primary goal
provide adequate ventilatory support
neuromuscular weakness vent management strategy (mode, Vt, rr, flow, PEEP)
Assist control or volume control
Vt 6-8mL/kg
rr 8-16
flow ≥ 60 L/min
PEEP ~ 5 cmH2O if needed
neuromuscular weakness vent management targets (Pplat, FiO2)
Pplat < 30 cmH2O
FiO2 may start at 21% if oxygenation normal
risk of neuromuscular weakness pt on vent
hypoventilation from muscle weakness
closed head injury vent management primary goal
protect airway and avoid worsening ICP
closed head injury vent management strategy (CO2)
avoid routine hyperventilation
temporary PaCO2 25-30 mmHg only for uncontrolled ICP, then gradual normalization
closed head injury vent risk
abrupt CO2 changes or excessive intrathoracic pressure affecting ICP
ARDS vent management primary goal
improve oxygenation while limiting VILI
ARDS vent management strategy (mode, PEEP, Vt)
PC-CMV or VC-CMV
PEEP to prevent collapse
Vt 6-8 mL/kg for mild-mod; Vt 4-6 mL/kg for mod-severe (lung-protective)
ARDS vent management targets (Pplat, SaO2)
Pplat < 30 cmH2O
SaO2 ~ 88-90%
ARDS risk for vent
overdistension, collapse, rapid CO2 rise
CHF/pulmonery edema vent management primary goal
reduce WOB and improve oxygenation/hemodynamics
CHF/pulmonary edema vent management strategy (mode, Vt, rr, flow, PEEP)
VC-CMV or PC-CMV
Vt 6-8 mL/kg
rr ≥ 10
flow ≥ 60L/min
PEEP 5-10 cmH2O
CHF/pulmonary edema vent management targets (FiO2, SpO2)
start FiO2 at 100%, titrate to SpO2 > 90-92%
CHF/pulmonary edema vent risk
hemodynamic effects of positive pressure (decrease venous return, hypotension)
Initial vent setup steps
verify orders: mode, Vt, rr, FiO2, PEEP, sensitivity
determine ABG goals
vent check: complete setup/calibration; leak test
bedside assessment
auscultation: BBS, ETT position
vital signs: HR, BP, SpO2, RR
alarms: set appropriately (pressure, volume, apnea)
diagnostics: ABG, CXR, relevant labs
frequency of pt-vent system checks
1-4 hrs (institution policy)
when to check pt-vent system
before/around ABG sampling
after vent changes or new orders
after transport/testing
during acute clinical changes
when vent performance is questionable
what to document on first vent system check
mode and sensitivity
Vt, rr, MV
tubing compliance and delivered Vt
alveolar ventilation and dead space considerations
pt response: vitals, comfort, synchrony
PIP
peak inspiratory pressure
influenced by resistance + compliance
Pplat
plateau pressure
marker of alveolar/static pressure; measured with insp hold
disease guidelines emphasize < 30 cmH2O
PTA
transairway pressure = PIP - Pplat
represents resistive pressure across airways
EEP/PEEP
end-expiratory pressure/positive end-expiratory pressure
relates to alveolar recruitment, oxygenation, and hemodynamics
increase PIP, unchanged Pplat =
increased RAW
secretions, bronchospasm, kink
increased PIP and increased Pplat =
decreased compliance
pulmonary edema, ARDS, pneumothorax
Static compliance equation
Cstatic = Vte / (Pplat - PEEP)
Static compliance focus
uses plateau pressure; reflects rsp system compliance under static conditions
Dynamic compliance equation
Cdyn = Vte / (PIP-PEEP)
dynamic compliance focus
uses peak pressure; affected by both resistance and compliance
Airway resistance equation
RAW = (PIP-Pplat) / flow (L/s)
airway resistance focus
resistive pressure difference relative to insp flow
interpretation of decreased Cstatic
stiff lungs
ARDS, fibrosis, edema
interpretation of decreased Cdyn with normal Cstatic
increased RAW
bronchospasm, secretions
interpretation of increased RAW
airway narrowing, obstruction, tube issues
lower infection point of the static pressure-volume curve marks
recruitment of large numbers of alveoli
clinical use of lower inflection point
set PEEP above this point to prevent collapse
upper inflection point of static pressure-volume curve indicates
onset of overinflation
clinical use of upper inflection point
keep Vt/pressure below this region to reduce VILI
what do you look at to monitor oxygenation/ventilation for vented pt
SpO2
ABGs
RR
what do you look at to monitor hemodynamics for vented pt
BP
cardiac output
HR
what do you look at to monitor vent mechanics
PIP
Pplat
PEEP
compliance
RAW
in an obstructive (COPD) case what would you examine first on vent
RR
Vt
flow
I:E ratio
presence of auto-PEEP
how can you increase expiratory time
decrease RR
increase flow
decrease Vt if large
adjust I:E (1:3 - 1:4)
what pt cases need longer expiratory time
obstructive cases
what can you adjust on vent to help an asthma case with permissive hypercapnia
aggressive normalization of PaCO2 requires high RR/Vt
if you increase RR or Vt on asthma case to blow off CO2 what is a risk you need to monitor
increased air trapping and pressures
what is the priority for an asthma case with permissive hypercapnia
maintain acceptable pH (≥ 7.2) and avoid barotrauma
in an ARDS case what are 3 vent parameters you want to focus on the most
Vt: low (4-6) to limit overdistention
PEEP: enough to prevent collapse and improve oxygentation
Pplat: keep < 30 cmH2O → balance oxygenation vs VILI
what steps do you take to assess an alarm case for an unstable pt
go to pt → assess breathing → disconnect and bag w/ 100% O2 → then check circuit, ETT, settings
what is the pattern and what would you assess in pt with high PIP but stable Pplat
pattern: increased RAW
assess: secretions, bronchospasm, kinks, water in tubing, ETT patency
what is the pattern in pt with high PIP and high Pplat
decreased compliance (asthma, ARDS, pneumothorax)
isolated PIP rise =
increased resistance
both PIP and Plat rise =
decreased compliance
PaO2 problem you would adjust what vent parameters
FiO2/PEEP
PaCO2 problem you would adjust what vent parameters
RR/Vt
simple fixes for increased RAW issue
suction - if secretions suspected
bronchodilator - if bronchospasm pattern
check circuit - remove water, unkink tubing
check ETT - reposition, bite block if needed
reduce insp flow - if flow is excessively high and causing turbulent resistance
lengthen exp time - if dynamic hyperinflation is contributing
simple fixes for decreased compliance issue
increase PEEP - improves recruitment
reduce Vt - lung-protective strategy
check for pneumothorax - tx if present
diuresis - if pulmonary edema suspected
prone positioning (ARDS)
recruitment maneuvers if appropriate
fix abdominal pressure (NG tube, repositioning)
P/F ratio formula
PaO2/FiO2
transairway pressure (PTA) formula
PIP - Pplat
Deadspace Ratio (VD/Vt) forumla
(PaCO2 - PeCO2) / PaCO2
x Vt = VD
Current Alveolar Vent (VA) / Alveolar Minute Volume (VE) formula
(Vt - VD) x RR
Cardiac Output (QT) forumla
SV x HR
Arterial Oxygen Content (CaO2) formula
(1.34 x SaO2 x Hb) + (0.003 x PaO2)
Total Oxygen Delivery (DO2) formula
CaO2 x QT x 10
Alveolar Gas Equation (PAO2)
FiO2 (PB - 47) - (PaCO2 / 0.8)