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Two theories of wolf to dog evolutionĀ
Humans selectively bred wolves for characteristics they wantedĀ
Human and wolf interactions increased and wolves with more amicable characteristics had better fitnessĀ
Dmitry Belyaev experiment
suggested that behavioral selection drove domesticationĀ
focused on tameness ā> social, unaggressiveĀ
Subject: silver foxes (related to dogs and never been domesticated)Ā
Procedure: based on tameness/response to humans, only some were allowed to reproduceĀ
Experiment ran for 30-35 generationsĀ
End population was very different from original foxes in temperament and behaviorĀ
Less fear responses to scary stimuliĀ
actively sought out human contact
Physical changes ā more white patches in coloring, floppier ears, curled tails, smaller featuresĀ Ā
Physiological changes ā lower stress, more serotonin, more offspring per liter, bred throughout the year (not seasonal)Ā
Tyron (1934) selective breedingĀ
Selectively bred rats for dull and bright rats at maze navigationĀ
dull rats made more errors
Cooper & Zubek (1958)Ā
Raised maze dull and maze bright rats in enriched and impoverished environmentsĀ
In enriched & impoverished environment, maze bright rats made fewer mistakes than maze dull ratsĀ
Difference between errors made by maze bright and maze dull rats was larger in impoverished environmentĀ Ā
Enriched environment overcomes genetic predispositionĀ
Longitudinal hemisphere
gap in middle of the brain that divides into right & left cerebral hemisphere
Sulcus/sulci
ridges/grooves in the brainĀ
Gyrus/gyri
raised bump in the brainĀ
Cerebral cortex (what it is + function)
outermost layer of the brainĀ Ā
Processing sensory information, movement and association areas (integrates thinking from other areas)
Frontal lobeĀ parts
Motor cortex:
Prefrontal cortex
Broca's area:
Motor cortex:
movementĀ
Primary motor cortex: cause movement in head and bodyĀ
Prefrontal cortex:
higher level cognitive functionsĀ
Decision-making, planning, acting for long-term goalsĀ
Broca's area:
language productionĀ
Parietal lobe ā location, purpose, and parts
separated from frontal lobe by central sulcusĀ
Language, spatial orientation, and attentionĀ
Primary somatosensory cortex:
Wernicke's area
Primary somatosensory cortex:
processes sensory motion and location of body in spaceĀ
Wernicke's area:
language comprehensionĀ
Temporal lobe: what it does and parts of it
higher order processing of visual memory, learning and memory and hearingĀ
Primary auditory cortex:
Hippocampus:
Amygdala:
Primary auditory cortex:
ability to control soundĀ
Hippocampus:
turns short term memory into long term memoryĀ
Amygdala:
processes fear and other emotionsĀ
Occipital lobe: purpose and part
visual processingĀ
Primary visual cortex:
Primary visual cortex:
main area for visual processingĀ
Cerebellum:
motor coordination and control, balance and posture, fine-tuning of voluntary movementsĀ
Corpus collosum:
connects left and right cerebral hemispheresĀ
Brain stem: purpose and parts
connects brain to spinal cordĀ
Midbrain:
Pons:
Medulla (lowest):
Midbrain purpose
produces dopamineĀ
Pons:
carry information to and from cerebellumĀ
Medulla (lowest):
regulates vital functions (e.g. cardiovascular and respiratory), very importantĀ
basal ganglia:
movement, habit formation, and reward processing
Thalamus:
relays sensory information heading to cerebral cortexĀ
Hypothalamus:
maintains homeostasis through regulating thirst, feeding, body temp, stress responseĀ
Pituitary gland:
produces many important hormones Ā
Pineal gland:
secrets hormone melatoninĀ
Ventricles:
system of cavities throughout the brain that produce CSF to regulate the environmentĀ
4 lobes
frontal, perietal, temporal, occipital
Function tools
CT and MRI and EEGĀ
Structure tools:
fMRI and PETĀ
CT:
takes images of soft tissues, bones, and organsĀ
MRI:
uses radio waves to create images of soft tissuesĀ
EEG:
less detailed measure of electric waves from brainĀ
fMRI:
shows blood flow to different parts of the brainĀ
PET:
drink dye that binds to blood cells and shows activation to different parts of brainĀ
CNS vs PNS
Central Nervous System (CNS): Brain and spinal cordĀ
Peripheral Nervous System (PNS): rest of body
Autonomic nervous system:
unconscious processesĀ
Sympathetic:
unconscious processes to perceive and act during dangerĀ
Heartrate increase, pupil dilation, digestion reductionĀ
Parasympathetic:
unconscious process to rest and digest after dangerĀ
Reduce heartrate, increase digestion, pupil constrictionĀ
Somatic nervous system:
voluntary movements and sensory informationĀ
Sensory neurons bringing information from peripheralsĀ
Motor neurons bringing information to cells in extremitiesĀ
relationship between nervous system and parts
Central Nervous System (CNS)Ā
Brain and spinal cordĀ
Peripheral Nervous System (PNS)Ā
Autonomic nervous system: unconscious processesĀ
Sympathetic: unconscious processes to perceive and act during dangerĀ
Heartrate increase, pupil dilation, digestion reductionĀ
Parasympathetic: unconscious process to rest and digest after dangerĀ
Reduce heartrate, increase digestion, pupil constrictionĀ
Somatic nervous system: voluntary movements and sensory informationĀ
Sensory neurons bringing information from peripheralsĀ
Motor neurons bringing information to cells in extremitiesĀ
MeningesĀ
Pia mater: shiny layer right on top of the brainĀ
Arachnoid mater: middle layerĀ Ā
Dura mater: outer layer to protect from outside damageĀ
right brain vs left brain
Right brain is more creative and time-freeĀ
Left brain is more logical and systematicĀ
Dendrites
ā shorter offshoots from cell bodyĀ
Axon ā
longer tail off neuronĀ
Myelin sheath ā
protective coating on outside of axonĀ
Axon terminals -
tips of the axon's branchesĀ
hormones vs neurotransmitters
Hormones can travel longer distances or short distances at different speedsĀ
Neurotransmitters always travel short distances very fastĀ
agonist vs antagonist
Receptor agonist: activates receptor by mimicking neurotransmitterĀ
Receptor antagonist: block receptorĀ
Opiate vs opioid drugsĀ
Opiate: naturally extracted or refined from plant matterĀ
Opium, Heroin, Morphine, CodeineĀ
Opioid: āsyntheticā drugs made in a lab, typically prescribedĀ
Hydrocodone, Oxycodone, FentanylĀ
how do opoid drugs work?
Opioid drugs inhibit pain signal for multiple steps in pathwayĀ
Bind to opioid receptors meant for endorphins, to mimic pain reduction, causing euphoriaĀ
Activates the reward pathway - VTA (Ventral Tegmental Area) & NA (Nucleus Accumbens)Ā
Excessive stimulation of the dopamine reward systemĀ
Stages of Neural DevelopmentĀ
Neurolation (formation of neural tube)Ā
Neurogenesis (creation) and proliferation (multiplication)Ā
Migration and differentiationĀ
Circuit formation (synaptogenesis)Ā
Circuit pruning (cell death and rearrangement)Ā
Acetylcholine (ACh)
Movement + memory
Glutamate
increases the likelihood that neurons will fire. Important for learning and memory
GABA
Main inhibitory neurotransmitter; decreases the likelihood that neurons will fire
Dopamine
Reward, motivation, reinforcement
Norepinephrine
Alertness, attention, arousal, flight or fight
Serotonin
Mood regulation, sleep
Endorphins
= pain relief + pleasure.