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Phase one of bone remodeling
Activation
What is attracted to the remodeling site in phase one
The Preosteoclasts
What do the preosteoclasts fuse together and form in phase one
Multinucleated osteoclasts
What is phase two of bone remodeling
Resorption
What do the osteoclasts dig out in phase two?
The resorption pit
What mineral gets in absorbed into the blood in resorption as the pit is being dug?
Calcium
What happens to the osteoclasts after the resorption pit is finished?
They disappear
What is phase three in bone remodeling
Reversal
What kind of cells appear along the pit in phase three?
Stem cells, osteoprogenitor cells
What do the stem cells do after they appear in the pit in phase three?
The multiply and differentiate and become osteoblasts
What is phase four of remodeling called
Formation
What is attracted to the surface of the resorption pit in phase four?
Osteoblasts
What do the osteoblast busy themselves with doing in phase four?
Replacing the removed bone tissue with osteoid
What is step five of remodeling called?
Quiescence or Resting
What becomes completely filled with osteoid in phase 5
The resorption pit
What occurs in phase five that forms hard bone?
The mineralization process
What gets trapped during mineralization in phase five?
Osteoblasts that mature into osteocytes
What do the new osteocytes in the matrix do in phase five?
Maintain the bone tissue
Abduction movement
Moving away from the midline of the body, legs separating
Adduction movement
moving towards the midline of the body, legs moving together
Flexation movement
Decreasing the angle between two body parts, forearm to upper arm
Extension movement
increasing the angle between two body parts, forearm away from upper arm
Rotation movement
In a pivot joint, head rotation
Osteoperosis
A condition in which the bone breaks down mineral content faster than it can rebuild it, causing weakened, softer, fragile bones.
What factors can lead to osteoperosis?
Aging, menopause, low testosterone, poor lifestyle
What is the first step of fracture healing?
Hematoma forms
in the first step of fracture healing, what is torn?
The blood vessels and the periosteum are torn
What forms as blood clots in step one of fracture healing?
hematoma within 6-8 hours
in step one of fracture healing, what begins to die without nutrition?
The bone cells
What is step two of fracture healing?
Soft callus forms
After a few days, what begins to form in step two of fracture healing?
New blood vessels
What begins to produce a bulging cartilage matrix in step two of fracture healing?
Chondroblasts
In step two of healing, what is the developing repair tissue called?
A soft callus, or temporary splint
What is step three of fracture healing called?
Soft callus ossifies into bone callus
After a week, what do osteoblasts do in step three of healing?
They produce osteoid and replace the soft callus with a hard one.
What happens after around two months in step three of healing?
The broken ends are firmly connected
What is step of four of fracture healing?
Bone remodeling
Why does bone remodeling have to occur in step four of healing?
To clean away excess bone callus and clean out the medullary cavity
What happens to osteoclasts during bone remodeling in step four of fracture healing?
They absorb injured and dead bone tissue.
What do osteoBLASTs do in bone remodeling in step four of healing?
They lay down new bone