Good and Poor Leaving Groups for Nucleophilic Substitution

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Last updated 9:28 AM on 10/11/26
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12 Terms

1
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what makes a good leaving group

When an atom is a weak base with a strong conjugate acid having a low pKa value.

2
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Going down a column of the periodic table, what happens to the basicity?

The basicity decrease and the leaving group ability increases

3
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going from LEFT to RIGHT what happens to the basicity?

basicity decreases and leaving ability increases

4
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Cl- is what kind of leaving group?

good leaving group

5
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Br- is what kind of leaving group?

good leaving group

6
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I- is what kind of leaving group?

good leaving group

7
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H2O is what kind of leaving group?

good leaving group

8
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F- is what kind of leaving group?

poor leaving group

9
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-OH is what kind of leaving group?

poor leaving group

10
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-NH2 is what kind of leaving group?

poor leaving group

11
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H- is what kind of leaving group?

Poor

12
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An R side group (nothing attached to the carbon) is what kind of leaving group

Poor leaving group