general pharma

Metabolism

Active drug to active form

FADS CP

Fluoxetine-norfluoxetine

Allopurinol-alloxanthine

Pro to active drug

PLASMA CCD

Levodopa-dopamine

ACE inh

Extra hep metabolism

Plasma esterase enzymes

Plasma pseudocholine esterase enzyme

Hoffman elimination-atracurium

Glu conjugation

Acetylation

UDP -GT

Paracetomal

S hydralizine Isoniazid procainamide dapsone

Irinotecan atazanavir

CYP inducers

CYP inhibitors

GRifampicin Antiepileptics SS

C Omeprazole KE Isonazid Valproate C GAR

Drug contraindicated in lactation

SMALL

Sulfonamides

Methotraxate

Aspirin

Lithium

Levitiracetam

Antibiotics causing contraceptive failure

DATA

Doxycycline

Ampicillin

Tetracycline

Amoxilline

OATP

OCTP

P gly

Penicillin cephalosporin

Tubocurare

Digoxin

Weak acidic poisoning

Aspirin

Acetaminophen

Methotraxate

Barbiturate

Weak basic drug poisoning

Amphetamine

Strychine

Morphine

Atropine

Quinine

Zero order drugs

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