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Dorzolamide ophthalmic (Trusport)

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Dorzolamide ophthalmic (Trusport)

Carbonic anhydrase inhibitor

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Brimonidine ophthalmic (Alphagan P)

Alpha agonist

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Timolol ophthalmic (Betimol, Timoptic)

Beta blocker, nonspecific (b1 + b2)

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Latanprost ophthalmic (Xalatan)

Prostaglandin analog

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Pioglitazone (Actos)

Thiazolidinediones (TZDs)

May cause or worsen CHF

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Metformin + sitagliptin (Janumet)

Biguanide + DPP4-I

May cause lactic acidosis

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Canagliflozin (Invokana)

SGLT2i

Increased risk of lower limb amputation

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Insulin glargine (Lantus, Basaglar, Toujeo)

Long acting insulin

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Insulin degludec (Tresiba)

Long acting insulin

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Insulin aspart (NovoLog)

Fast acting insulin

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Dulaglutide (Trulicity)

GLP-1 RA

Thyroid C-Cell tumor risk

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Glimepiride (Amaryl)

Sulfonylureas

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13

Insulin lispro (Humalog)

Short acting insulin

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Liraglutide (Victoza)

GLP-1 RA

CI in patients with certain thyroid or endocrine cancers

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15

Sitagliptin (Januvia)

DPP4i

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Glipizide (Glucotrol)

Sulfonylurea

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Linagliptin (Tradjenta)

DPP4i

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18

Insulin detemir (Levemir)

Long acting insulin

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19

Metformin (Glucophage)

Biguanide

May cause lactic acidosis

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Acyclovir (Zovirax, Sitavig)

Antiviral, purine nucleoside

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Cefdinir (Omnicef)

3rd gen cephalosporin

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22

Valacyclovir (Valtrex)

Antiviral

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Hydroxychloroquine (Plaquenil)

Disease modifying antirheumatic drug (DMARD)

Prescriber must be familiar with complete prescribing guidelines before use

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Clindamycin (Cleocin)

Lincosamide

Risk of severe diarrhea and C. Diff

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Fluconazole (Diflucan)

Triazole antifungal

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Levofloxacin

Fluoroquinolone antibiotic

May increases risk of tendonitis and tendon ruptures especially in elderly

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27

Mupirocin (Centany)

Topical antibiotic

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Nitrofurantoin (Furdantin, Macrodantin, Macrobid)

Imidazolidinedione

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29

Metronidazole (Flagyl)

Nitroimidazole 1st gen

Carcinogenic in mice - avoid necessary use

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Amoxicillin (Amoxil, Moxatag)

Penicillin antibiotic (beta-lactam)

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Azithromycin (Zithromax)

Macrolide antibiotic

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Doxycycline (Doryx, Monodox, Periostat, Vibramycin)

Tetracycline antibiotic

Risk of severe diarrhea and C. Diff

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Cephalexin (Keflex)

1st gen cephalosporin

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Amoxicillin + Clavulanate (Augmentin)

Penicillin antibiotic (beta-lactam)

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Oseltamivir (Tamiflu)

Antiviral, influenza

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Ciprofloxacin (Cipro)

Fluoroquinolone antibiotic

May increase risk of tendonitis and tendon ruptures especially in the elderly

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Sulfamethoxazole + trimethoprim (Bactrim, Septra, Sulfatrim)

Sulfonamide antibiotic

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Minocycline (Minocin, Solodyn)

Tetracycline antibiotic

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Ketoconazole (Nizoral, Extina, Xolegel)

Antifungals

Do not use unless other drugs do not work, severe hepatotoxicity, heart arrhythmias, and severe drug interactions

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Cyanocobalamin (Vitamin B12)

Vitamin B12

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Potassium Chloride (Klor-Con, Micro-K)

Electrolytes

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Vitamin D (ergocalciferol [D2], cholecalciferol [D3])

Vitamin D

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Ferrous sulfate (Feosol, Fer-in-Sol, Slow FE, Feratab)

Iron supplement

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Folic acid

Vitamin B9

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45

Albuterol + ipratropium (Combivent Respimat, DuoNeb)

Beta 2 agonist, short acting (SABA) + muscarinic antagonist, short acting (SAMA)

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Budesonide inhaled (Pulmicort Respules/Flexhaler)

Inhaled Corticosteroid

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Levoceterizine (Xyzal)

2nd generation antihistamine

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Albuterol inhaled (Proventil HFA, Ventolin HFA, Proair HFA)

Short acting beta-2 agonists (SABA)

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Montelukast (Singulair)

Leukotriene inhibitor

Serious neuropsych events. Including agitation, aggression, depression, hallucinations, suicidal thoughts, etc.

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Fluticasone inhaled (Flovent Diskus/HFA)

Inhaled corticosteroid

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51

Cetirizine (Zyrtec)

2nd gen antihistamine

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52

Budesonide + formoterol inhaled (Symbicort)

Long acting beta-2 agonist (LABA) + corticosteroid

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Fluticasone + salmeterol inhaled (Advair Diskus/HFA, Wixela)

Long acting beta-2 agonist (LABA) + corticosteroid

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Loratadine (Claritin)

2nd gen antihistamine

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Tiotropium inhaled (Spiriva HandiHaler/Respimat)

Long acting muscarinic antagonist (LAMA)

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Benzonatate (Tessalon)

Antitussive, non-narcotic

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Tamsulosin (Flomax)

Alpha-1 receptor antagonist

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Finasteride (Proscar, Propecia)

5-alpha-reductase inhibitor

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Oxybutynin (Ditropan XL)

Antispasmodic, urinary

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Prednisone (Sterapred)

Corticosteroid

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Levothyroxine (Synthroid, Levoxyl, Levothroid)

Thyroid hormone

Not to be used for weight loss

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62

Thyroid (Armour thyroid, Nature-Thyroid, Westhroid)

Natural thyroid hormone

Not to be used for weight loss

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Testosterone topical (Androgel, Androderm, Axiron, Fortesta)

Testosterone hormone

Children should avoid contact with unwashed or unclothed application sites

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Progesterone (Prometrium, Crinone, Procheive, Endometrin)

Progestion, non-contraceptive

Do not use in CV disease or dementia. Increased risk of breast cancer

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Norethindrone (Camila, Errin, Jolivette)

Oral contraceptive, progestin only

Cigarette smoking increases the risk of MI and stroke

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Liothyronine (Cytomel, Triostat)

Thyroid hormone

Not to be used for weight loss

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67

Ethinyl estradiol + norethindrone (Junel, Loestrin)

Oral birth control

Cigarette smoking increases the risk of serious CV side effects. Increases with age over 35.

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68

Estradiol (Estrace)

Estrogen hormone replacement

May increase the risk of endometrial cancer, stroke, MI, and breast cancer - May increase the risk of dementia in post menopausal women

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Ethinyl estradiol + etonogestrel (NuvaRing)

Intrauterine/vaginal contraceptive

Cigarette smoking increases the risk of serious CV side effects. Increases with age over 35

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Ethinyl estradiol + desogestrel (Apri, Enskyce)

Oral birth control

Cigarette smoking increases the risk of serious CV side effects. Increases with age over 35

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71

Ethinyl estradiol + norgestimate (Sprintec, Tri-Sprintec)

Oral birth control

Cigarette smoking increases the risk of serious CV side effects. Increases with age over 35

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72

Ethinyl estradiol + levonorgestrel (Amethyst, Aviane, Falmina)

Oral birth control

Cigarette smoking increases the risk of serious CV side effects. Increases with age over 35

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73

Alendronate (Fosamax)

Bisphosphonate

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74

Methylprednisolone (Medrol)

Corticosteroid

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75

Hydrocortisone (Cortef, Cortizone, Hytone, Cortenema, Proctocort)

Corticosteroid

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76

Prednisolone (Orapred, Pediapred)

Corticosteroid

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77

Triamcinolone topical (Kenalog)

Topical corticosteroid

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78

Adalimumab (Humira)

TNF inhibitor

Increased risk of serious infections. Lymphoma or other malignancies may also occur.

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79

Methotrexate (Otrexup, Rasuvo, Trexall)

Antimetabolites, folate analog

Only for severe disease. Fetal death/birth defects. Impaired drug elimination. Hepatotoxicity. Pulmonary toxicity. Malignant lymphoma. Skin reactions

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80

Dicyclomine (Bentyl)

Anticholinergic

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81

Polyethylene glycol (MiraLax, GlycoLax)

Osmotic laxative

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82

Docusate (Colace [sodium], Surfak [calcium])

Emollient laxative

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83

Ondansetron (Zofran)

5HT3 RA

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84

Promethazine (Phenergan)

1st gen antihistamine

CI in pts <2 years old - injection can cause severe tissues damage; caution advised

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85

Pantoprazole (Protonix)

PPI

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86

Omeprazole (Prilosec)

PPI

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87

Esomeprazole (Nexium)

PPI

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88

Famotidine (Pepcid)

H2 blocker

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89

Ibuprofen (Advil, Motrin)

NSAID

May increase risk of CV thrombotic events - May increase risk of fatal GI events

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90

Meloxicam (Mobic)

NSAID

May increase risk of CV thrombotic events - May increase risk of fatal GI events

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91

Naproxen (Naprosyn, Naprelan)

NSAID

May increase risk of CV thrombotic events - May increase risk of fatal GI events

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92

Celecoxib (Celebrex)

COX-2 inhibitor (NSAID)

May increase risk of CV thrombotic events - May increase risk of fatal GI events

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93

Diclofenac (Voltaren)

NSAID

May increase risk of CV thrombotic events - May increase risk of fatal GI events

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94

Ketorolac (Toradol, Sprix)

NSAID

Oral - up to 5 days of treatment and only after parenteral use

All - May increase risk of CV thrombotic events - May increase risk of fatal GI events

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95

Tramadol (Ultram, ConZip, Qdolo)

Opioid agonist

High addiction/misuse risk

Opioid analgesic REMS

Life threatening respiratory depression can occur

Concomitant use with BZD

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96

Morphine sulfate (Kadian, Morphabond, MS Contin)

Opioid agonist

High abuse potential - May lead to dependency and respiratory depression may occur even at accepted dosing - Adverse CV events and death reported on misuse

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97

Hydrocodone + APAP (Norco, Lotab)

Opioid combo + non-narcotic

Avoid doses of APAP >4000mg per day (associated with cases of acute liver failure)

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98

Oxycodone (OxyContin, Roxicodone, Xtampza ER)

Opioid agonist

High addiction/misuse risk

Opioid analgesic REMs

Life threatening respiratory depression can occur

Concomitant use with BZD

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99

Butalbital + APAP (Fioricet, Alizital, Bupap, Phrenilin)

Pain reliever and relaxant combination

Avoid doses of APAP >4000mg per day (Associated with cases of acute liver failure)

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Colchicine (Colcrys, Mitigare, Gloperba)

Anti-gout

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