bug drug coverage

what bugs do natural penicillins cover

o Strep

o Enterococci

o Treponema pallidum

name the 2 aminopenicillins

Ampicillin

Amoxicillin

what bugs do aminopenicillins cover

o Step

o Enterococci

o Listeria

o E. coli

o Klebsiella

o H. influenzae

name the anti staphylococcal penicillins

Nafcillin

Oxacillin

Dicloxacillin

what bugs do the antistaphylococcal penicillins cover

o Staph

o Strep

o MSSA

what bugs do unsyn and augmentin cover

o strep

o enterococci

o staph

o E. coli

o Klebsiella

o Listeria

o H. influenzae

o N. gonorrhoeae

o Proteus

o Bacteroides

what bugs does pip/tazo cover

o strep

o enterococci

o staph

o E. coli

o Klebsiella

o Listeria

o H. influenzae

o N. gonorrhoeae

o Proteus

o Bacteroides

pseudomonas

name the first generation cephalosporins

cephalexin, cefadroxil, cefazolin

what bugs do first gen cephalosporins cover

o Strep

o Staph

1. MSSA

o Some E. coli and Kleb

what are first gen cephalosporins the DOC for

MSSA

name the second gen cephalosporins

cefuroxime, cefoxitin, cefprozil, cefaclor, cefotetan

what bugs do second gen cephalosporins cover

o Strep

o Staph

o E. Coli

o Kleb

o H. influenzae

o M. Catarrhalis

o Cefoxitin and cefotetan - some anaerobic activity

name the third gen cephalosporins

Ceftriaxone

Ceftazidime

Cefotaxime

Cefpodoxime

Cefdinir

Cefixime

bug coverage of third gen cephalosporins

1. Staph

2. S. pneumo

3. E. coli

4. Kleb

5. H. Influenzae

6. M. catarrhalis

ceftazadime covers pseudomonas

name the fourth generation cephalosporins

cefepime

bugs covered by fourth gen cephalosporinso

o staph

o strep

o E. coli

o Kleb

o H. influenzae

o M. catarrhalis

o Pseudomonas

o Enterobacter spp

cefepime is the DOC for

enterobacter

name the fifth generation cephalosporins

ceftaroline

bugs that fifth generation cephalosporins cover

o Staph - MRSA

o Strep

o E. Coli

o Kleb

o H. influenzae

o M. Catarrhalis

what bug does ceftolozane/tazobactam cover

pseudomonas

what bug does ceftazidim/avibactam cover

ESBL

what bug does cefepime/enmetazobactam cover

ESBL and pseudomonas

what bug does cefiderocol cover

SPACE and ESBL

what bug does ceftobiprole cover

ESBL

name the carbapenems

imipenem, meropenem, ertapenem, doripenem

bugs that are covered by carbapenems

o Staph

o Strep

o Entero -> imipenem only

o E. coli

o Kleb

o H. influenzae

o M. Catarrhalis

o Pseudomonas -> all but ertapenem

name the one monobactam

aztreonam

name the bugs covered by aztreonam

o E. coli

o Kleb

o H. influenzae

o M. catarrhalis

o Pseudomonas

name the bug covered by sulbactam/durlobactam

acinetobacter baumanii

name the glycopeptides

Vancomycin

Telavancin

Dalbavancin

Oritavancin

what bugs do the glycopeptides cover

o Staph

1. MRSA

o Strep

Entero

what are glycopeptides the DOC for

MRSA

what bugs does daptomycin cover

o Staph

1. MRSA

o Strep

o Entero

1. VRE

what is daptomycin the DOC for

MRSA, VRE

name the streptogramins and oxazolidinones

quinupristim/dalfopristin, linezolid, tedizolid

what bugs do the streptogramins and oxazolidinones cover

o Staph

1. MRSA

o Strep

o entero

1. VRE

what are streptogramins and oxazolidinones the DOC for

MRSA, VRE

name the aminoglycosides

gentamicin, tobramycin, amikacin

what bugs do the aminoglycosides cover

o Staph synergy

o Strep synergy

o Entero synergy

o E. coli

o Kleb

o H. influenzae

o M. catarrhalis

o Pseudomonas

name the fluoroquinolone

Ciprofloxacin

Levofloxacin

Moxifloxacin

what bugs does ciprofloxacin cover

1. Some staph and entero

2. E. coli and Kleb

3. H. flu and M. cat

4. Atypicals

5. pseudomonas

what bugs does levofloxacin cover

1. Some staph and entero

2. E. coli and Kleb

3. H. flu and M. cat

4. Atypicals

5. strep

6. pseudomonas

what bugs does moxifloxacin cover

1. Some staph and entero

2. E. coli and Kleb

3. H. flu and M. cat

4. Atypicals

5. strep

6. Anaerobes

what bugs do baxdela cover

MRSA, pseudomonas

name the macrolides

Azithromycin

Clarithromycin

Erythromycin

what bugs do macrolides cover

o Atypicals

o Strep

o Some H. flu

o Some mycobacteria

what bugs does TMP/SMX cover

o Staph

1. CA-MRSA

o Strep

o E coli, kleb

o H. flu, M. Cat

what bugs do tetracyclines cover

o Staph

1. CA-MRSA

o Strep

o H. flu, M. Cat

Atypicals

what is TMP/SMX the DOC for

CA-MRSA

what are tetracyclines the DOC for

CA-MRSA

what bugs does tigecycline cover

o staph

1. MRSA

o Strep

o Entero

o E. coli, kleb

o H. flu, M. cat

o Anaerobes

o Atypicals

what is tigecycline the DOC for

MRSA

what bugs do metronidazole cover

o Anaerobes (more gram -)

1. Bacteroides

what bugs does clindamycin cover

o staph

1. CA-MRSA

o Strep

o Anaerobies (more gram +)

what is clindamycin the DOC for

CA-MRSA

what bugs does rifamycins cover

o Staph

o N. meningitidis

o H. flu

Mycobacteria

what bugs does polymyxin cover

o Pseudomonas

o A. baumanii

list the drugs that are the DOC for CA-MRSA

TMP/SMX, tetracyclines, clindamycin

list the drugs that are the DOC for MRSA

Vanco, linezolid, daptomycin

list the drugs that are DOC for MSSA

anti-staphylococcal penicillins, first gen cephalosporins

list the drugs that do NOT cover staph

natural penicillins, aminopenicillins, metronidazole, aztreonam

name the drugs that do not cover strep

metronidazole, aztreonam

name the drugs that cover enterococci

-natural penicillins

-aminopenicillins

-beta lactam/BLI

-pip-tazo

-imipenem

-aminoglycosides

-vanco

-linezolid

-daptomycin

-tigecycline

name the drugs that cover pseudomonas

-pip/tazo

-ceftazadime

-cefepime

-carbapenems minus ertapenem

-aztreonam

-cipro

-levo

-aminoglycosides

what drug is the DOC for enterococci

aminopenicillins

what is the DOC for VRE

linezolid, daptomycin

what are the DOC for anaerobes

clindamycin, flagyl

what drugs cover atypicals

fluoroquinolones, macrolides, tetracyclines, tigecycline

what drugs cover all gram (-) minus psudomonas (E. coli, Kleb, H. flu, M cat

-beta lactam/BLI

-pip-tazo

-2nd-5th gen cephalosporins

-carbapenems

-aztreonam

-quinolones

-TMP/SMX

-tigecycline