Phosphodiesterase type 5 inhibitors (PDE-5 inhibitors)

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Class of medications that interfere with certain types of chemical reactions in your blood -- this helps blood vessels relax, reduces inflammation and more

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Sildenafil

Viagra

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Tadalafil

Cialis

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What are the indications of Phosphodiesterase type 5 inhibitors (PDE-5 inhibitors)?

Male erectile dysfunction

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What are the adverse drug reactions of Phosphodiesterase type 5 inhibitors (PDE-5 inhibitors)?

Headache, Flushing, Priapism

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What happens when Phosphodiesterase type 5 inhibitors (PDE-5 inhibitors) are co-administered with nitrates?

Severe hypotension, drug interaction can result in death and combination is contraindicated