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Unit #2 - Biology
What is Digestion?
The process of breaking down food to provide nutrients and energy for growth, repair, and reproduction
What is Ingestion?
The process of taking food, drink, or another substance into the body by swallowing or absorbing it
What is Absorption?
The transfer of digested nutrients from the digestive system to the bloodstream
What is Egestion?
The removal of waste food materials from the body
What is the Pathway for food? (In order)
1. Mouth
2. Esophagus
3. Stomach
4. Small Intestine
5. Large Intestine
6. Rectum
7. Anus
What are enzymes?
A substance that acts as a catalyst in living organisms, regulating the rate at which chemical reactions proceed without itself being altered in the process.
What are enzymes role in the body?
Enzymes are biological catalysts that accelerate chemical reactions in the body, enabling essential processes like digestion, metabolism, DNA replication, and detoxification.
What are the two digestion types?
Mechanical Digestion & Chemical Digestion
What is a mechanical digestion?
The act of physically breaking up food into smaller pieces
Goal: To create as much surface area as possible so that digestive enzymes can interact with more of it at once -> gets broken down faster
Ex: Chewing, crushing, squishing, squeezing, smashing, liquifying
What is a chemical digestion?
The act of breaking down food at the molecular level (breaking the chemical bonds)
Goal: Release the energy stored in these bonds to use in the body
Ex: Using enzymes to catalyze (speed the reaction rate), catabolize, cleave (break) bonds, transfer energy)
Where does Ingestion occur?
The mouth
- Ingestion (as food enters the mouth)
- Digestion also begins in the mouth via
breakdown of food molecules by your teeth (Mechanical)
breakdown of food molecules by your saliva (Chemical)
- Absorption
Some small substances (ex. medication, vitamins) can enter the bloodstream through sublingual capillaries (blood vessels under the tongue)
The Mouth - Saliva, Teeth & Tongue
Saliva
- Dissolve food particles to. taste food
- Contain mucus (lubricate), water (soften food), amylase (breaks amylose)
Front teeth
Incisors & Canines → Grab and cut food
Back teeth
Premolars & Molars → Broad flattened teeth for grinding and crushing food
Tongue
Rolls food into “bolus" and contain taste buds
(Bolus - mixture of saliva and food)
★ Ingestion
★ Digestion

The Esophagus, Pharynx & Trachea
Esophagus
Long tube lined with epithelial tissue, surrounded by smooth muscle tissue
Bolus stretches the walls of the esophagus
Undergo contractions called peristalsis (Helps the bolus move down esophagus to the stomach)
Epiglottis
A lid/flap that covers the trachea during swallowing
Ensures food goes through the esophagus instead of the lungs (Trachea, air pipe)
Pharynx
Two way structure, allows air to travel to the lungs and food to travel down the esophagus
★ No Digestion
The Esophagus - Sphincters
Sphincters
Circular muscles that contract to close an opening in the body
Gastro Esophageal
Located between esophagus & stomach
Keeps the food & acid from moving up the esophagus
Pyloric Sphincter
The Stomach
Stomach
Muscular, J shaped, Sac-like organ, food is temporarily stored
Stomach walls churn and squeeze mixture
★ Mechanical Digestion
Stomach Acid (Approximately 2L released/day)
Gastric juice (Made of hydrochloric acid (HCl), digestive enzymes, acid and mucus)
Break up proteins from the food (Break the peptide bonds in protein)
Mucus protects stomach lining from acid damage
Acid (pH 2-3) kills most bacteria / microorganisms
★ Chemical Digestion
The Stomach - Enzymes
Stomach Enzymes
Convert inactive enzyme (pepsinogen) to active form (pepsin)
Pepsin enzyme (a protein) require a highly acidic environment (low pH)
Breaks down other proteins into amino acids
★ Chemical Digestion
The Stomach - 4 Layers
Mucosa
The innermost layer is an extensively folded layer.
Secrets the gastric juice, epithelial cells divide rapidly to replace & heal damaged stomach lining
Entire stomach lining is replaced every three days
Submucosa
A layer of connective tissue that contains a networks of nerves and blood vessels.
Muscularis (3 muscle layer)
Consists of smooth muscles, contracts frequently
Mixes food w/ gastric juice to produce “Chyme”
★ Chyme - Pulpy acidic fluid mixed w/ gastric juice & food materials
Serosa
The smooth outermost layer of the stomach
Holds the stomach in place
Secretes lubricating fluid, eliminates friction between organs