CHB Wk1 Hormone Paths

Gonadotropic Releasing Hormone (GnRH)

FSH, LH → ovaries and testes

Corticotropin Releasing Hormone (CRH)

Adrenocorticotrophin (ACTH) → adrenal gland → cortisol

Thyrotropin Releasing Hormone (TRH)

Thyroid Stimulating Hormone (TSH) → thyroid → T4 → T3

Growth Hormone Releasing Hormone (GHRH)

Growth Hormone → liver → IGF-1

Dopamine

stops prolactin production

DIO1

liver, kidneys: T4 → T3

DIO2

pituitary feedback regulation: T4 → T3

DIO3

brain, placenta: T4 → rT3

cortisol

regulates metabolism, immunosuppressant

growth hormone

stimulates growth of bone and tissues, promotes protein synthesis

thyroid hormone (T4 and T3)

regulates basal metabolic rate, heart rate, and BP

aldosterone

increases sodium resorption at the kidney → water retention

prolactin

stimulates milk production and breast development

parathyroid hormone

increases osteoclast activity

antidiuretic hormone

promotes water resorption in kidneys (aquaporin 2), raises blood pressure