Pharm Legal, Ethical And Cultural considerations

Ethnopharmacology

Understanding specfic impact of cultural factors on pt drug response

Biologic Variations for African cultural group

Keloids, sickle cell, lactose intolerance

Biologic Variations of Asian Groups

Many Drug Interactions, Lactose intolerance, thalassemia

Biologic Variations of Native americans

Lactose intolerance, cleft uvula problems

Biologic Variations of Hispanic groups

Lactose intolerance

Pharmacogemomics

How certain genetic traits effect drug response

Drug polymorphism

Effect of pts age, gender,size, body comp etc on pharmacokinetics of specific drugs

Expedited Drug approval

“Fast track drug approval” AIDS got 1st expedited approval, covid was 2nd

Black Box Warning

Pattern of adverse drug events. warning must be presented to pt when prescibed

Controlled substances

Schedule I has high potential for abuse and no medical use (heroin,LSD) Schedule V Has lowest potential for abused (cold medicine)

Negligence

Failure to provide care

Malpractice

Failure to provide appropriate care which leads to injury