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Surface area to volume ratio
High surface area to volume ratio: These organisms have a large surface area relative to their volume so the diffusion of the substances is fast as there is a small diffusion distance to the centre
Low surface area to volume ratio: These organisms have a small surface area relative to their volume ratio so the diffusion of substances is slower, and so specialised exchange surfaces are needed
reduces the area available for diffusion per unit time
Multicellular organisms require specialised surfaces
-In single-celled organisms, substances diffuse directly across the cell membrane.
-This cannot happen in multicellular organisms because:
Cells are not in direct contact with the external environment.
Diffusion distances between cells and their environment are large.
Larger organisms have higher metabolic rates, so they need more oxygen and glucose.
-To solve this problem, multicellular organisms have evolved specialised exchange surfaces.
There are two linked levels of exchange:
At an exchange surface, substances move between the external and the internal environment of the organism
At an individual cell, substances move between tissue fluid and the inside of the cell by crossing its plasma membrane
Metabolic rate
-Metabolic rate- the amount of energy expended by an organism within a time period
-Basal metabolic rate (BMR)- metabolic rate of an organism when at rest
-Metabolic rate is measured using different methods and apparatus:
Oxygen consumptions (Respirometers)
Carbon dioxide production (Carbon dioxide probe)
Heat production (Calorimeter)

Features of specialised exchange surfaces
-Large surface area to volume ratio
-Thin- short diffusion pathway
-Partially permeable- osmosis
-Movement of the environmental medium- eg. air
-Movement of the internal environmental medium, eg. blood

Ways to increase surface area to volume ratio
-Folding in the surface of the cell membrane to increase the surface area
-Developing into long, thin, or elongated shaped cells
-Presence of large vacuoles inside the cell that pushes the other organelles to the side of the cell for easier diffusion of materials.