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11 Terms

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gene therapy

a technique for correcting abnormal genes responsible for disease development

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genetic engineering

the permanent introduction of one of more new or altered genes into a cell, tissue, or organism

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stem cells

unique, unspecialized cells that can make identical copies of themselves for long periods of time

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autosomes

homologous chromosomes that are exactly alike in length, shape, and the genes they carry

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sex chromosomes

determine a person’s biological sex

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chromosomal abnormality

any change in the chromosome number or structure compared to what is typical for a species

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locus(plural loci)

the physical location of a gene on a chromosome

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recessive genetic disorders

include several thousand human genetic disorders that are inherited as recessive traits on autosomes

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genetic carriers of a disorder

carry the disorder allele(a) and do not have the disease

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dominant genetic disorders

an inherited disease caused by an autosomal dominant allele(A), rarer than autosomal recessive disorders

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pedigree

a chart similar to a family tree, shows genetic relationships among family members over two or more generations of a family’s medical history and used to identify and differentiate the inheritance patterns of different traits or disorders