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gene therapy
a technique for correcting abnormal genes responsible for disease development
genetic engineering
the permanent introduction of one of more new or altered genes into a cell, tissue, or organism
stem cells
unique, unspecialized cells that can make identical copies of themselves for long periods of time
autosomes
homologous chromosomes that are exactly alike in length, shape, and the genes they carry
sex chromosomes
determine a person’s biological sex
chromosomal abnormality
any change in the chromosome number or structure compared to what is typical for a species
locus(plural loci)
the physical location of a gene on a chromosome
recessive genetic disorders
include several thousand human genetic disorders that are inherited as recessive traits on autosomes
genetic carriers of a disorder
carry the disorder allele(a) and do not have the disease
dominant genetic disorders
an inherited disease caused by an autosomal dominant allele(A), rarer than autosomal recessive disorders
pedigree
a chart similar to a family tree, shows genetic relationships among family members over two or more generations of a family’s medical history and used to identify and differentiate the inheritance patterns of different traits or disorders