P3 Spring Key Drugs Exam Black Box (ID/MSK/GI)

Loperamide Hydrochloride (Imodium A-D) BBW

Torsades de pointes and sudden death

Sodium phosphate BBW

Contains aluminum - may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum.

Gentamicin sulfate BBW

'Risk of Toxicities especially Nephrotoxicity, Ototoxicity, Neurotoxicity

fetal harm when administered to a pregnant woman

Ciprofloxacin hydrochloride (Cipro, Ciloxan) BBW

Serious adverse reactions (tendinopathy and tendon rupture, peripheral neuropathy, and CNS effects); exacerbation of myasthenia gravis

Levofloxacin (Levaquin) BBW

'Serious adverse reactions (tendinopathy and tendon rupture, peripheral neuropathy, and CNS effects); exacerbation of myasthenia gravis

Vancomycin hydrochloride (Vancocin) BBW

'Embryo-fetal toxicity due to excipients

Clindamycin (Cleocin) BBW

Colitis (systemic)

Metronidazole (Flagyl, Metrogel) BBW

Carcinogenic