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Endothermic Reactions (Anabolic Reactions)
Put together small to large molecules, use free energy, and store it in new molecules (e.g., dehydration synthesis)
Exothermic Reactions (Catabolic Reactions)
Break down large to small molecules and release free energy (e.g., hydrolysis)
Metabolism
Sum of all anabolic & catabolic reactions (or endothermic & exothermic reactions)
Reaction Speed
Increased by increasing temperature or concentration
ATP (Adenosine Triphosphate)
Chemical energy used to store & release energy in the cell
Oxidation Reaction
Removes electrons (usually on hydrogen) and releases free energy
Reduction Reaction
Gains electrons and gains energy
ATP Structure
Adenine, sugar (ribose), and 3 phosphate groups
Energy Storage & Release in ATP
Breaking the bond between the 2nd & 3rd phosphate groups releases energy; forming a bond stores energy
Goal of Enzymes
To break apart larger molecules to use monomers & get energy out of bonds in between monomers
Enzyme
Catalyst that speeds up reactions by bringing reactants together & aligning them to react; not used up in the reaction
Activation Energy
Energy required for a reaction to begin (lowered by catalysts)
Denature
Disrupt folding, which messes up the function
Non-competitive Inhibition
Molecule attaches to an enzyme (not at the active site) and causes a shape change so the substrate can't bind
Competitive Inhibition
Molecule other than the substrate blocks the active site so the substrate can't insert
Enzyme Activity Changes
Active site changes due to temperature or pH changes, so the substrate can't bind
Trypsin (Digestion)
Secreted by pancreas into small intestine; macromolecule: proteins -> amino acids
Pepsin (Digestion)
Utilized in stomach; macromolecule: proteins -> amino acids
Amylase (Digestion)
Utilized in mouth/saliva; macromolecule: starch -> simple sugar
Lipase (Digestion)
Produced in mouth, stomach, pancreas; utilized in small intestine; macromolecule: lipids -> fatty acid & glycerol
Nuclease (Digestion)
Produced in pancreas & small intestine; utilized in small intestine; macromolecule: nucleic acids -> nucleotides
Large Intestines (Colon)
End of tract; reabsorbs water, absorbs vitamins produced by bacteria, and eliminates feces/waste products
Intracellular Digestion
Digestion inside the cell (found in plants & single-celled organisms)
Extracellular Digestion
Digestion takes place outside cells (found in most animals)
Human Digestion
Break down macromolecules in order to be absorbed & used as matter & energy
Mechanical / Physical Digestion
Physically break food into smaller pieces
Chemical Digestion
Enzymes break food into smaller molecules to be absorbed
Mouth (Digestive System)
Part of the digestive system/tube itself; contains teeth (mechanical) and saliva (chemical)
Saliva
Contains salivary amylase that begins to break down starch to disaccharide
Epiglottis
Flap that blocks trachea to prevent food & water from entering lungs
Esophagus
2 layers of muscle connecting pharynx to stomach; uses peristalsis (muscle contractions) to move food
Stomach
3 layers of smooth muscle; mechanical digestion via muscle contractions to churn food; chemical digestion via gastric glands
Mucus (Stomach)
Lubricates and protects stomach lining from acids & enzymes
Hydrochloric Acid (HCl)
Activates enzymes, dissolves minerals, & kills bacteria
Pepsin (Stomach)
Breaks complex proteins to smaller polypeptides & amino acids
Sphincters
Thick ring of muscle that opens & closes to allow food in & out of the stomach
Cardiac Sphincter
Lower esophageal sphincter between esophagus & stomach (top of stomach)
Pyloric Sphincter
Between stomach & small intestine (bottom of stomach)
Liver
Not part of digestive tract; stores glycogen, detoxifies substances from blood, and secretes bile to help break up fat droplets
Gallbladder
Stores bile until required for digestion
Pancreas
Not part of digestive tract; secretes pancreatic fluid (digestive enzymes) into small intestines and neutralizes acid/pH from stomach
Small Intestine
Receives secretions from gallbladder & pancreas to complete digestion; consists of duodenum, jejunum, and ileum
Villi
Finger-like projections lining the small intestine that increase surface area and contain blood vessels & lymph to absorb water & nutrients