bone remodeling (out of order)

do this in addition to writing it out in the flow systems work sheet !!!

where nothing happens

resting state

where osteoclasts attach to bone surface

reabsorption

where an acidic environment is created

reabsorption

where mineral component of bone matrix is dissolved

reabsorption

where the degradation of natural matrix occurs

reabsorption

where the reabsorption pit is formed

rebasorption

what causes the formation of the reabsorption pit

degradation of organic matrix

where calcium is released and levels regulated

reabsorption

where mononuclear cells appear on surface of bone

reversal

end of reabsorption phase and start of formation phase

reversal

osteoblasts create new osteoid at reabsorption site

formation

not a stage:

unmineralized bone matrix is called the…

osteoid

replenishes bone lost during reabsorption phase

osteoblasts in

formation phase

where osteoid mienralizes

mineralization

calcium and phosphate from body fluid crystallize onto collagen fibers of osteoid

mineralization

not a stage:

where new bone is hardened to strengthen mechanical strength and support

mineralization

not a stage:

tubular structure that makes up compact bone

osteons

not a stage:

cells that maintain bone and can sense physical stress

osteocytes

not a stage:

what is the physiological purpose of bone breakdown

releases needed minerals

not a stage:

what regulates calcium released from bones and its disposition back into them

hormones from the endocrine system

not a stage:

essential for activation of muscle contraction

calcium

building and breaking is important for BLANK bones

strengthening

write the 6 stages of bone remodeling in order

resting state

reabsorption

reversal

formation

mineralization

the first state of bone remodeling is the….

resting state

after resting state comes ….

reabsorption

after reabsorption its …

reversal

after reversal is…

formation

after formation is….

mineralization

describe what happens in the resting state

nothing

describe what happens in the reabsorption phase

osteoclasts attach to bone and create acidic environment to dissolve minerals in bone matrix

which forms reabsorption pit

calcium is released

describe what happens in the reversal phase

mononuclear cells appear on surface of bone

define mononuclear cells

signal end of absorption phase and stat of formation phase

describe what happens in the formation phase

osteoblasts create osteoids at the reabsorption site

define osteoid

unmineralized bone matrix

describe what happens during the mineralization phase

osteoid mineralizes

calcium and phosphate chrystalize onto collagen fibers of osteoid which hardens into new bones