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Mental illness perspective
Encompasses medical perspective and roles of neurological factors like brain chemistry/structures
Disease model
Medical doctors often consider psychological problems as essentially biologically based diseases and are likely to prescribe medication as the sole treatment
Mental disorder(perspective of american psychiatric association)
Syndrome characterized by clinically significant disturbance in an individual’s cognition, emotional regulation, or behavior that reflects a dysfunction in the psychological, biological, or developmental processes underlying mental functioning
Simplified → includes biological processes but is not solely due to biological processes; treatments include both medications and psychotherapy
Causes of psychological disorders
Disorders are heterogenous → complex and multi-causal and different factors may contribute to a disorder in different people
Predisposing causes
Genetic, early life experiences
Precipitating causes
Stress like loss, break ups, or trauma
Maintaining causes
Withdrawal from others, negative cognitions, or self deprecation(turns off others)
How does predisposition interact with precipitating factors?
They are inversely related
DSM-V
Classification scheme for specific categories of mental disorders
Key qualities of DSM-V
Reliability and validity
Psychosis
Person loses touch with reality and may experience hallucinations/delusions
Neurosis
Person experiences anxiety/fear/distress but knows what is real and can recognize their unreasonable thoughts/fears
Internalizing disorders
Person directs their struggle inward
ex.) depression, social anxiety, anxiety, phobias
Externalizing disorders
Person expresses their struggles outwardly through actions/behaviors
ex.) OCD or ADHD
Psychotic disorders
Mental disorders involving a loss of contact with reality through hallucinating, delusions, or disorganized thinking
ex.) schizophrenia
Psychotic features
When symptoms of psychosis occur as part of another mental disorder
ex.) person with severe depression also experiences psychosis
Hallucination
Seeing or sensing something that isn’t there
ex.) hearing voices or seeing things
Delusions
Believing something that isn’t true
ex.) believing aliens are following you
Personality disorders
Include patterns of thinking, feeling, or behaving in ways that are unhealthy in everyday life
ex.) narcissistic, antisocial, borderline, avoidant, or ocd
Two major mood disorders
Depressive(prolonged and intense feeling of too down with sadness/irritability) and bipolar(prolonged and intense feeling of too up with elation/sadness)
Major depressive disorder
5 symptoms present in same 2 week period
Symptoms include feeling sad/worthless/hopeless, low energy, unable to concentrate, sleep problems, appetite problems, no pleasure, or thoughts of death
Persistent depressive disorder(dysthymia)
Less severe but chronic at least 2 symptoms persisting over a 2 year period
Disruptive mood dysregulation disorder
Category for children 6-18
Symptoms present in at least 2 settings for at least 12 months with no more than a 3 month period without all symptoms =
Includes severe recurring temper outbursts and angry/irritable moods(3 times a week)
Premenstrual dysphoric disorder
Depressive symptoms occurring severely before menstruation
Bipolar disorder(I)
Manic periods of extreme energy/activity/racing thoughts and no sleep, prolonged elation/grandiose, risky and poorly planned behavior, and usually a major depression episode(NOT required)
Bipolar II
Hypomanic episode and a major depression episode(REQUIRED)
Cyclothymic disorder(less severe)
Milder symptoms, less impairment, and at least 2 years duration
Mood disorder seasonal patterns
Winter → depression
Spring → mania
Biochemistry of unipolar depression
Disturbance in the neural pathways that use monoamines(serotonin, norepinephrine, and dopamine) as their primary neurotransmitter
→ depression is associated with reduced activity of monoamines, especially serotonin
→ mania/bipolar may be due to increased norepinephrine/dopamine and decreased serotonin
Antidepressant drugs…
Increase post-synaptic activity of monoamines(prozac,zoloft,lexapro)
SSRIs
Selective serotonin reuptake inhibitors → increase serotonin activity
Symptom relief is delayed for about 2-3 weeks
Wellbutrin
Other drugs used to treat depressive disorder; not an SSRI but affects dopamine/norepinephrine neurons(also for smoking cessation)
Medications for bipolar disorder
Lithium → weight gain, tremors, kidney damage
Mood stabilizers like carbamazepine or abilify
Seroquel → helps lower mania and helps with depressive episodes
ECT
Electro convulsive therapy
Used for severe depression
Not used commonly as the side effects are crazy
Major depressions brain structure
Low frontal lobe(left) activity
Increased activity in the amygdala(like anxiety disorders)
Twin studies on genetic factors on depression
Genetics are important but STRESS is necessary for genetic liability to be manifested into depression
Major stressor in depression is…
LOSS(of loved one, social network, friends, health, job)
→ high social support can buffer the effects of LOSS
Loss + low social support = closely associated with depression
Beck’s Cognitive Theory of Depression
Vulnerability to depression is associated with a cognitive style characterized by a negative view of self, world or future
→ results from distorting experiences so that they always lead to negative implications
→ maxing failure, minimizing success, arbitrary inference
Seligman’s Hopelessness Theory of Depression
Tendency to attribute failures to stable(no change) and global (is widespread)
→ leads a person to person to feel like they are helpless to change anything
Best medication for depression
Combination of antidepressants(medication) and cognitive therapy(psychotherapy)
→ empirically supported therapies(cognitive CBT therapy), interpersonal therapy
→ important additional factors - increasing support, activity, exercise
Anxiety disorders
Marked by excessive feelings of fear and anxiety
Anxiety = response to a vague or less clearly specified threat
Fear = response to a specific perceived threat
Generalized Anxiety Disorder
Relatively constant experience of anxiety that is not directly associated with any specific threat
→ excessive worry, problems sleeping, nervous/physiologically aroused
Biology of generalized anxiety disorder
Overactivated amygdala and reduced neurotransmitter (GABA)
→ associated with childhood trauma/stress, inhibited temperament
Cognitive in generalized anxiety disorder
Excessive worry and increased attention to potential threat(vigilant)
Treatment with generalized anxiety disorder
Relaxation and coping skills
Drugs → benzodiazepines (mild tranquilizers) like valium and xanax(affects GABA receptors) or Buspar(affects serotonin system)
Specific phobia
Irrational fear and active avoidance of feared specific stimulus/situation
→ treat with exposure therapies
Social anxiety disorder
Treat with exposure therapies and SSRIs
Panic disorder
Treat with CBT and relaxation and SSRIs
Agoraphobia
Treat with CBT, exposure therapies, and SSRIs
OCD
Treated with SSRIs or exposure/response prevention
Positive symptoms
Adding something → like delusions and hallucinations
Negative symptoms
Missing something → absence of affect, no speech
Cognitive symptoms
Poor sustained attention and low working memory capacity
Schizophreniform disorder
Same as schizophrenia just shorter duration(< 6 months)
1/3 recover
Drugs for Schizophrenia
Drugs that block dopamine activity → most effective at reducing psychotic symptoms
Drugs that increase dopamine activity → produce a temporary schizophrenic like symptoms
LSD does NOT mimic Schizophrenia
Neuroleptics
Reduce positive symptoms → phenothiazines(chlorpromazine/thorazine) or butyrophenomes(aldol)
New generation drugs
Reduce negative symptoms → clozapine or risperidone
Dissociative identity disorder
Two+ distinct personalities that alternate dominance (multiple personalities)
Mostly occurs in women
Somatoform disorders
Occurrence of physical symptoms are not due to any physical disease process
Hypochondriasis
Preoccupied with health and worried about getting sick