Lipids galing kay maam

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35 Terms

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Lipids are classified into Fatty Acids, Glycerides, Nonglyceride Lipids, and Complex Lipids (Lipoproteins).

Classification of Lipids

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Fatty Acids

Lipids categorized into Saturated and Unsaturated fatty acids.

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Glycerides

Lipid esters containing glycerol and fatty acids, divided into Neutral glycerides and Phosphoglycerides.

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Nonglyceride Lipids

Lipids not derived from glycerol, including Waxes, Sphingolipids, and Steroids.

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Complex Lipids

Lipids that include Lipoproteins.

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Saturated Fatty Acids

Long-chain monocarboxylic acids with the general formula CH3(CH2)nCOOH, where n in biological systems is an even integer.

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Example of Saturated Fatty Acid Formula

If n = 16 in CH3(CH2)nCOOH, the formula yields an 18-carbon saturated fatty acid.

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Unsaturated Fatty Acids

Fatty acids that contain one or more double bonds.

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Palmitoleic Acid

An unsaturated fatty acid with formula CH3(CH2)5CH=CH(CH2)7CO2H and a melting point of 0°C.

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Oleic Acid

An unsaturated fatty acid with formula CH3(CH2)7CH=CH(CH2)7CO2H and a melting point of 13°C.

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Linoleic Acid

An unsaturated fatty acid with formula CH3(CH2)4(CH=CHCH2)2(CH2)6CO2H and a melting point of -5°C.

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Linolenic Acid

An unsaturated fatty acid with formula CH3CH2(CH=CHCH2)3(CH2)6CO2H and a melting point of -11°C.

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Arachidonic Acid

An unsaturated fatty acid with formula CH3(CH2)4(CH=CHCH2)4(CH2)2CO2H and a melting point of -49°C.

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Esterification

Reaction where fatty acids react with an alcohol to form esters and water.

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Acid Hydrolysis

The reverse reaction of esterification that produces fatty acids from esters.

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Saponification

Base-catalyzed hydrolysis of an ester.

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Neutral Glycerides

A type of glyceride that is nonionic and nonpolar.

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Phosphoglycerides

A type of glyceride with molecules that have a polar region and a phosphate group.

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Sphingolipids

Lipids that are not derived from glycerol, are amphipathic (containing a polar head group and two nonpolar fatty acid tails), and are derived from sphingosine.

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Sphingosine

A long-chain, nitrogen-containing (amino) alcohol that serves as the backbone for sphingolipids.

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Sphingomyelins

Sphingolipids located throughout the body that serve as an essential structural component of nerve cell membranes.

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Waxes

A diverse group of organic compounds that are water-resistant, lipophilic ("fat-loving"), and solid or malleable at room temperature with melting points typically above 40°C (104°F).

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Lanolin

A wax used as a protective coating for hair and skin, as well as in skin creams and ointments.

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Carnauba Wax

A wax used as automotive polish.

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Whale Oil (Spermaceti Wax)

A wax used in ointments and candles.

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Prostaglandins in Reproductive System

PGE2 stimulates muscle contraction, particularly uterine contractions, with increased levels noted immediately before labor onset.

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Prostaglandins in Gastrointestinal Tract

Inhibits acid secretion and increases secretion of a protective mucus layer into the stomach.

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Prostaglandins in Kidneys

Prostaglandins produced in the kidneys cause renal blood vessels to dilate.

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Cortisone Function

Important to the proper regulation of a number of biochemical processes.

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Cortisone Medical Uses

Used in treating rheumatoid arthritis, asthma, gastrointestinal disorders, skin conditions, and a variety of other diseases.

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Cortisone Possible Effects

Fluid retention, sodium retention, and potassium loss.

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Cortisone Side Effects

Muscle weakness, osteoporosis, peptic ulcers, vertigo, headache, and convulsions.

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Tay-Sachs Disease

A rare, fatal, inherited neurodegenerative disorder.

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Cause of Tay-Sachs Disease

Caused by a mutation in the HEXA gene on chromosome 15.

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Enzyme Deficiency in Tay-Sachs Disease

Deficiency of the enzyme beta-hexosaminidase A (Hex A).