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Lipids are classified into Fatty Acids, Glycerides, Nonglyceride Lipids, and Complex Lipids (Lipoproteins).
Classification of Lipids
Fatty Acids
Lipids categorized into Saturated and Unsaturated fatty acids.
Glycerides
Lipid esters containing glycerol and fatty acids, divided into Neutral glycerides and Phosphoglycerides.
Nonglyceride Lipids
Lipids not derived from glycerol, including Waxes, Sphingolipids, and Steroids.
Complex Lipids
Lipids that include Lipoproteins.
Saturated Fatty Acids
Long-chain monocarboxylic acids with the general formula CH3(CH2)nCOOH, where n in biological systems is an even integer.
Example of Saturated Fatty Acid Formula
If n = 16 in CH3(CH2)nCOOH, the formula yields an 18-carbon saturated fatty acid.
Unsaturated Fatty Acids
Fatty acids that contain one or more double bonds.
Palmitoleic Acid
An unsaturated fatty acid with formula CH3(CH2)5CH=CH(CH2)7CO2H and a melting point of 0°C.
Oleic Acid
An unsaturated fatty acid with formula CH3(CH2)7CH=CH(CH2)7CO2H and a melting point of 13°C.
Linoleic Acid
An unsaturated fatty acid with formula CH3(CH2)4(CH=CHCH2)2(CH2)6CO2H and a melting point of -5°C.
Linolenic Acid
An unsaturated fatty acid with formula CH3CH2(CH=CHCH2)3(CH2)6CO2H and a melting point of -11°C.
Arachidonic Acid
An unsaturated fatty acid with formula CH3(CH2)4(CH=CHCH2)4(CH2)2CO2H and a melting point of -49°C.
Esterification
Reaction where fatty acids react with an alcohol to form esters and water.
Acid Hydrolysis
The reverse reaction of esterification that produces fatty acids from esters.
Saponification
Base-catalyzed hydrolysis of an ester.
Neutral Glycerides
A type of glyceride that is nonionic and nonpolar.
Phosphoglycerides
A type of glyceride with molecules that have a polar region and a phosphate group.
Sphingolipids
Lipids that are not derived from glycerol, are amphipathic (containing a polar head group and two nonpolar fatty acid tails), and are derived from sphingosine.
Sphingosine
A long-chain, nitrogen-containing (amino) alcohol that serves as the backbone for sphingolipids.
Sphingomyelins
Sphingolipids located throughout the body that serve as an essential structural component of nerve cell membranes.
Waxes
A diverse group of organic compounds that are water-resistant, lipophilic ("fat-loving"), and solid or malleable at room temperature with melting points typically above 40°C (104°F).
Lanolin
A wax used as a protective coating for hair and skin, as well as in skin creams and ointments.
Carnauba Wax
A wax used as automotive polish.
Whale Oil (Spermaceti Wax)
A wax used in ointments and candles.
Prostaglandins in Reproductive System
PGE2 stimulates muscle contraction, particularly uterine contractions, with increased levels noted immediately before labor onset.
Prostaglandins in Gastrointestinal Tract
Inhibits acid secretion and increases secretion of a protective mucus layer into the stomach.
Prostaglandins in Kidneys
Prostaglandins produced in the kidneys cause renal blood vessels to dilate.
Cortisone Function
Important to the proper regulation of a number of biochemical processes.
Cortisone Medical Uses
Used in treating rheumatoid arthritis, asthma, gastrointestinal disorders, skin conditions, and a variety of other diseases.
Cortisone Possible Effects
Fluid retention, sodium retention, and potassium loss.
Cortisone Side Effects
Muscle weakness, osteoporosis, peptic ulcers, vertigo, headache, and convulsions.
Tay-Sachs Disease
A rare, fatal, inherited neurodegenerative disorder.
Cause of Tay-Sachs Disease
Caused by a mutation in the HEXA gene on chromosome 15.
Enzyme Deficiency in Tay-Sachs Disease
Deficiency of the enzyme beta-hexosaminidase A (Hex A).