3pd top200 fall boxed warnings and pregnancy categories

addiction, abuse, accidental ingestion, neonatal withdrawal, alcohol, cyp3a4/ interactions, hepatotoxicity, concurrent benzodiazpine

hydrocodone box warning

addiction, abuse, accidental ingestion, neonatal withdrawal, alcohol, cyp3a4/ interactions, hepatotoxicity, concurrent benzodiazpine

apap/hydocodone box warning

addiction, abuse, misuse, respiratory depression, accidental ingestion, neonatal withdrawal, cyp3a4/5 interaction, concurrent benzodiazepine

oxycodone box warnings

abuse, respiratory depression, accidental ingestion, neonatal withdrawal, interaction with cyp3a4/5, 2d6, avoid benzos/cns depressants, med error risk with oral solution

apap/codeine box warning

respiratory depression, addiction, cyp3a4/5, fatalities in children, care with disposal, formulations not interchangeable, concurrent benzos/cns, neonatal withdrawal, heat exposure with patch

fentanyl box warning

ethanol, addiction, respiratory depression, neonatal withdrawal, accidental ingestion, concurrent benzos

morphine box warning

addiction, respiratory depression, accidental ingestion, cyp2d6 in children, neonatal withdrawal, concurrent benzos

tramadol box warning

none

buprenorphine/naloxone box warning

avoid abrupt d/x of intrathecal product

baclofen box warning

none

cyclobenzaprine box warning

none

methocarbamol box warning

none

tizandine box warning

none

carisoprodol box warning

cv events, gi toxicity, cabg

ibuprofen box warning

cv/thrombotic events, serious gi bleeding/perf, cabg

meloxicam box warning

cv risk, gi risk, thrombotic events

naproxen box warning

cardiotoxicity, ci perioperatively for cabg, ci in seirous gi disorders

celecoxib box warning

cv risk, gi risk, cabg

diclofenac sodium box warning

none

lidocaine box warning

none

hydrocortisone box warning

none

methylprednisolone box warning

none

prednisolone box warning

none

prednisone box warning

none

triamcinolone box warning

none

sumatriptan box warning

none

alendronate box warning

none

allpurinol box warning

none

lantanoprost box warning

none

brimondine box warning

none

cetirizine box warning

none

folic acid box warning

none

hydroxychloroquine box warning

none

meclizine box warning

bone marrow suppression, renal impairment, hepatoxicity, pneumonitis, gi toxicity, secondary malignancy, tumor lysis syndrome, dermatologic toxicity, opportunistic infections radiotherapy, hypersensitivity, pregnancy,

methotrexate box warning

none

oxybutynin box warning

none

solifenacin box warning

none

tolterodine box warning

none

phentermine box warning

none

sidentafil box warning

none

tadalafil box warning

none

sucralfate box warning

suggested risk for steroids

hydrocodone pregnancy category

suggested risk

apap/hydrocodone pregnancy category

suggested risk

oxycodone pregnancy category

suggested risk

apap/codeine pregnancy category

suggested risk

fentanyl pregnancy category

suggested risk for opioids

morphine pregnancy category

suggested risk

tramadol pregnancy category

none

buprenorphine/naloxone pregnancy category

suggested risk

baclofen pregnancy category

none

cyclobenzaprine pregnancy category

none

methocarbamol pregnancy category

none

tizandine pregnancy category

none

carisoprodol pregnancy category

suggested risk in 1st and 3rd trimester for all nsaids

ibuprofen pregnancy category

suggested risk in 1st and 3rd trimester

meloxicam pregnancy category

suggested risk in 1st and 3rd trimester

naproxen pregnancy category

suggested risk in 1st and 3rd trimester

celecoxib pregnancy category

suggested risk in 1st and 3rd trimester

diclofenac pregnancy category

none

lidocaine pregnancy category

suggested risk

hydrocortisone pregnancy category

none

methylprenisolone pregnancy category

suggested risk

prednisolone pregnancy category

suggested risk

prednisone pregnancy category

none

triamcinolone pregnancy category

none

sumatriptan pregnancy category

none

alendronate pregnancy category

none

allopurinol pregnancy category

none

latanoprost pregnancy category

none

brimonidine pregnancy category

none

certirizine pregnancy category

none

folic acid pregnancy category

none

hydroxychloroquine pregnancy category

none

meclizine pregnancy category

contraindicated

methotrexate pregnancy category

none

oxybutynin pregnancy category

none

solifenacin pregnancy category

none

tolerodine pregnancy category

contraindicated

phentermine pregnancy category

none

sidenafil pregnancy category

none

tadalfil pregnancy category

none

sucralfate pregnancy category