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what is the amino acid that is always in every third position
glycine
what is the name of the collagen helix
polyproline helix
what is formed in the first stage of collagen formation
procollagen
what terminus does the formation of collagen helix start from
C-terminus
what is the name of the enzyme that cleaves the terminals of procollagen
procollagen peptidase
what is the name of the structure that is formed after the cleavage of procollagen
tropocollagen
how long is tropocollagen
300nm
which residues form covalent crosslinks between tropocollagen subunits
lysine
what enzyme helps to form a reactive aldehyde form of lysine
lysyl oxidase
what is the name of the link between an aldehyde and amino group
lysinorleucine
what is the name of the link between two aldehyde groups
aldol
what is the type of collagen found in skin, bone, tendon
Type 1
what is the type of collagen found in cartilage
type 2
what is the type of collagen found in blood vessels
type 3
what is the type of collagen found in basement membranes
type 4
what is the anchor protein of type 4 collagen
laminin
what are the components of the basement membrane that interact
type 4 collagen, nidogen, laminin, heparan sulfate
which type of collagen gene is mutated in osteogenesis imperfecta
type 1
Which residue in collagen is replaced by cysteine in osteogenesis imperfecta
glycine
what is scurvy caused by
vitamin C deficiency
what is the enzyme that is hindered in scurvy
prolyl hydroxylase
consumption of what seed leads to Lathyrism
sweet pea
what chemical compound do sweet peas contain making them toxic
beta-aminopropionitrile
what kind of charge do proteoglycans have
negative
what are repeating subunits of disaccharide proteoglycans called
glycosamioglycans
what are the different types of crosslinks in elastin
desmosine, lysinonorleucine, aldol
what is the name of the type of helix elastin has
beta-spiral