Collagen, Proteoglycans, Elastin

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27 Terms

1
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what is the amino acid that is always in every third position

glycine

2
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what is the name of the collagen helix

polyproline helix

3
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what is formed in the first stage of collagen formation

procollagen

4
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what terminus does the formation of collagen helix start from

C-terminus

5
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what is the name of the enzyme that cleaves the terminals of procollagen

procollagen peptidase

6
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what is the name of the structure that is formed after the cleavage of procollagen

tropocollagen

7
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how long is tropocollagen

300nm

8
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which residues form covalent crosslinks between tropocollagen subunits

lysine

9
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what enzyme helps to form a reactive aldehyde form of lysine

lysyl oxidase

10
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what is the name of the link between an aldehyde and amino group

lysinorleucine

11
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what is the name of the link between two aldehyde groups

aldol

12
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what is the type of collagen found in skin, bone, tendon

Type 1

13
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what is the type of collagen found in cartilage

type 2

14
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what is the type of collagen found in blood vessels

type 3

15
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what is the type of collagen found in basement membranes

type 4

16
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what is the anchor protein of type 4 collagen

laminin

17
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what are the components of the basement membrane that interact

type 4 collagen, nidogen, laminin, heparan sulfate

18
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which type of collagen gene is mutated in osteogenesis imperfecta

type 1

19
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Which residue in collagen is replaced by cysteine in osteogenesis imperfecta

glycine

20
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what is scurvy caused by

vitamin C deficiency

21
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what is the enzyme that is hindered in scurvy

prolyl hydroxylase

22
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consumption of what seed leads to Lathyrism

sweet pea

23
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what chemical compound do sweet peas contain making them toxic

beta-aminopropionitrile

24
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what kind of charge do proteoglycans have

negative

25
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what are repeating subunits of disaccharide proteoglycans called

glycosamioglycans

26
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what are the different types of crosslinks in elastin

desmosine, lysinonorleucine, aldol

27
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what is the name of the type of helix elastin has

beta-spiral