Benzodiazepines

BZD in insomnia

( Mn - T E FLon)

Temazepam

Triazolam

Estazolam

Flurazepam

Teratogenic BZD

( Mn - Flu Te)

Flurazepam

Temazepam

BZD in alc withdrawal syndrome

( Mn - C>>OD)

Chlordiazepoxide

Oxazepam

Diazepam

Z - drugs affinity

(Z1 - alpha 1; Z3 - alpha 2,3)

Eszopiclone - alpha 2,3

Zolpidem, zaleplon - alpha 1

Z drugs use

(3 - eszolpiclone, 1 - zolpidem, zaleplon)

3 - long - chronic insomnia & maintainance

1 - short - sublingual : midnight awakening ; controlled release : short term rx

Melatonin agonist in insomnia

("Melteon" drugs - B T S)

Blind people insomnia

TASImelteon

Smith magenis syndrome

RAmelteon

Orexin(+ wakefulness) antagonist

("Orex ant" drugs )

SUVorexant

LEMBorexant

BZD in Lennox-Gastaut syndrome

(Mn - Lets Go Start Class)

Clobazam

Date rape drug

Mn - Date Night(NIT)

FluNITrazepam

BZD safe in liver failure

(Mn: L O T S)

Lorazepam (+ renal failure)

Oxazepam

Temazepam

eStazolam

BZD near delivery

Floppy baby syndrome