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Afferent nerves
Nerves that carry sensory signals (nerve impulses) toward the central nervous from the periphery.
Aphasia
Loss of language function.
Arachnoid mater
Middle layer of the meninges named for the spider-web-like trabeculae that extend between it and the pia mater.
Astrocyte
Glial cell type of the central nervous system that provides support for neurons and maintains the blood-brain barrier.
Autonomic nervous system (ANS)
Functional division of the nervous system that is responsible for homeostatic reflexes that coordinate control of cardiac and smooth muscle, as well as glandular tissue.
Axon
Single process of the neuron that carries an electrical signal (action potential) away from the cell body toward a target cell.
Axon hillock
Tapering of the neuron cell body that gives rise to the axon.
Axon segment
Single stretch of the axon insulated by myelin and bounded by nodes of Ranvier at either end.
Axon terminal
End of the axon, where there are usually several branches extending toward the target cell.
Axoplasm
Cytoplasm of an axon, which is different in composition than the cytoplasm of the neuronal cell body.
Babinski sign
Dorsiflexion of the foot with extension and splaying of the toes in response to the plantar reflex, normally suppressed by corticospinal input.
Bipolar
Shape of a neuron with two processes extending from the neuron cell body-the axon and one dendrite.
Blood-brain barrier (BBB)
Physiological barrier between the circulatory system and the central nervous system that establishes a privileged blood supply, restricting the flow of substances into the central nervous system.
Brain
The large organ of the central nervous system composed of white and gray matter, contained within the cranium and continuous with the spinal cord.
Brain stem
Region of the adult brain that includes the midbrain, pons, and medulla oblongata.
Broca's area
Region of the frontal lobe associated with the motor commands necessary for speech production.
Brodmann's areas
Mapping of regions of the cerebral cortex based on microscopic anatomy that relates specific areas to functional differences.
Cauda equina
Bundle of spinal nerve roots that descend from the lower spinal cord below the first lumbar vertebra.
Caudate
Nucleus deep in the cerebrum that is part of the basal nuclei.
Central nervous system (CNS)
Anatomical division of the nervous system located within the cranial and vertebral cavities, namely the brain and spinal cord.
Central sulcus
Surface landmark of the cerebral cortex that marks the boundary between the frontal and parietal lobes.
Cephalgia
Pain in the head.
Cerebellum
Region of the adult brain connected primarily to the pons that is largely responsible for comparing information from the cerebrum with sensory feedback.
Cerebral angiography
Process of recording the blood vessels of the cerebrum.
Cerebral cortex
Outer gray matter covering the forebrain, marked by wrinkles and folds known as gyri and sulci.
Cerebrum
Region of the adult brain that is responsible for higher neurological functions such as memory, emotion, and consciousness.
Cerebral hemisphere
One half of the bilaterally symmetrical cerebrum.
Cerebrospinal fluid (CSF)
A colorless fluid produced by the brain that cushions the brain and spinal cord.
Cerebral thrombosis
Formation of a blood clot in a blood vessel within the skull.
Choroid plexus
Specialized structure containing ependymal cells that line blood capillaries and filter blood to produce cerebrospinal fluid.
Corpus callosum
Large white matter structure that connects the right and left cerebral hemispheres.
Dendrite
One of many branchlike processes that extends from the neuron cell body and functions as a contact for incoming signals.
Descending tract
Central nervous system fibers carrying motor commands from the brain to the spinal cord or periphery.
Diencephalon
Region of the adult brain that includes the thalamus and hypothalamus.
Direct pathway
Connections within the basal nuclei that disinhibit the thalamus to increase cortical control of movement.
Dorsal (posterior) nerve root
Axons entering the posterior horn of the spinal cord.
Dura mater
Tough, fibrous, outer layer of the meninges that surrounds the entire central nervous system.
Efferent nerves
Nerve tissue that carries impulses away from the CNS towards the peripheral resulting in motor response.
Electroencephalogram
The record of electrical activity of the brain.
Electroencephalography
Process of recording the electrical activity of the brain.
Embolus
An obstruction such as a blood clot or plaque that blocks the flow of blood in an artery or vein.
Encephalitis
Inflammation of the tissues of the brain.
Encephalomalacia
Softening of the tissues of the brain.
Enteric nervous system (ENS)
Neural tissue associated with the digestive system that is responsible for nervous control through autonomic connections.
Ependymal cell
Glial cell type in the central nervous system responsible for producing cerebrospinal fluid.
Epithalamus
Region of the diencephalon containing the pineal gland.
Foramen magnum
Large opening in the occipital bone of the skull through which the spinal cord emerges.
Frontal lobe
Region of the cerebral cortex directly beneath the frontal bone of the cranium.
Ganglion
Localized collection of neuron cell bodies in the peripheral nervous system.
Ganglionectomy
Excision of a ganglion.
Glial cell
One of the various types of neural tissue cells responsible for maintenance of the tissue.
Glioblastoma
A central nervous system tumor composed of developing glial tissue.
Glioma
A tumor that begins in the glial tissue.
Gray matter
Regions of the nervous system containing cell bodies of neurons with few or no myelinated axons.
Gyrus
Ridge formed by convolutions on the surface of the cerebrum or cerebellum.
Hemiplegia
Paralysis on one side of the body.
Hemorrhagic stroke
Disruption of blood flow to the brain caused by bleeding within the cranial vault.
Hydrocephalus
The abnormal buildup of cerebrospinal fluid in the ventricles of the brain.
Hyperesthesia
Increased sensitivity to stimuli.
Hypothalamus
A region of the forebrain below the thalamus; has function in both the autonomic and endocrine systems.
Ischemic stroke
Disruption of blood flow to the brain because blood cannot flow through blood vessels.
Integration
Nervous system function that combines sensory perceptions and higher cognitive functions to produce a response.
Initial segment
First part of the axon as it emerges from the axon hillock, where the electrical signals known as action potentials are generated.
Longitudinal fissure
A large separation along the midline between the two cerebral hemispheres.
Lumbar puncture
Procedure used to withdraw cerebrospinal fluid from the lower lumbar region of the vertebral column.
Medulla oblongata
A part of the brain stem responsible for control of heart rate and breathing.
Meninges
The membranes that surround the central nervous system.
Meningioma
A tumor of the meninges.
Meningitis
Inflammation of the meninges, the tough membranes that surround the central nervous system.
Meningocele
Protrusion of the meninges.
Meningomyelocele
Protrusion of the meninges and spinal cord.
Microglia
Smaller than most of the other glial cells; they ingest and digest cells or pathogens that cause disease.
Midbrain
A portion of the brainstem, positioned above the pons, also called mesencephalon, that assists in motor reflexes associated with visual, auditory, and somatosensory stimuli.
Mononeuropathy
Disease affecting a single peripheral nerve.
Motor nerves
Peripheral, efferent, myelinated nerve tissue that stimulates muscle contraction.
Multipolar
Shape of a neuron that has multiple processes-the axon and two or more dendrites.
Myelin sheath
Lipid-rich layer of insulation that surrounds an axon, formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system; facilitates the transmission of electrical signals.
Nerves
Bundle of fibers that receives and sends messages between the body and the brain.
Neuralgia
Pain of the peripheral or cranial nerves.
Neuritis
Inflammation of a peripheral or cranial nerve.
Neuroglia
Supportive tissue of the nervous system, including the network of branched cells in the central nervous system (astrocytes, microglia, and oligodendrocytes) and the supporting cells of the peripheral nervous system (Schwann cells and satellite cells), also called glia.
Neurologist
A doctor who has special training in diagnosing and treating disorders of the nervous system.
Neurology
A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.
Neuroma
Tumor made up of nerve cells.
Neuron
Cells that propagate information via electrochemical impulses.
Neuropathy
A nerve problem that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body.
Neurotransmitters
Chemicals that are made by nerve cells and used to communicate with other cells, including other nerve cells and muscle cells.
Node of Ranvier
Gap between two myelinated regions of an axon, allowing for strengthening of the electrical signal as it propagates down the axon.
Nucleus
The cell's central organelle, which contains the cell's DNA.
Occipital lobe
Region of the cerebral cortex directly beneath the occipital bone of the cranium.
Olfaction
The sense of smell.
Oligodendrocyte
Glial cell type in the central nervous system that provides the myelin insulation for axons in tracts.
Paresis
Partial paralysis wherein there is still some control of the muscles.
Paresthesia
Abnormal sensation in the extremities.
Parietal lobe
Region of the cerebral cortex directly beneath the parietal bone of the cranium.
Peripheral nervous system (PNS)
All nervous tissue that is outside of the brain and spinal cord.
Pia mater
Thin, innermost membrane of the meninges that directly covers the surface of the central nervous system.
Poliomyelitis
Acute infection by the poliovirus, especially of the motor neurons in the spinal cord and brainstem.
Polyneuritis
Inflammation of several peripheral nerves at the same time.
Polyneuropathy
Disease of multiple peripheral nerves at the same time.