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staphylococcus aureus is a gram ___ bacteria
positive
is staphylococcus part of the normal flora? if so, where?
Yes, anterior nares, nasopharynx, perineum, skin
oxygen requirements for staphyloccus aureus
facultative anaerobe
staphylococcus virulence factors
catalase, coagulase, capsule, protein A, hyaluronidase, hemolysins, exfoliative toxins, toxic-shock syndrome toxin, enterotoxins, beta-lactamase, salt-tolerant
what type of infections does staphylococcus aureus cause?
Food poisoning, TSS, soft tissue infections, impetigo, scalded skin syndrome (Ritter's disease), endocarditis, osteomyelitis
staphylococcus aureus shape
cocci, grapelike clusters
are staphylococcus aureus bacteria motile?
no
staphylococcus epidermidis is a gram ___ bacteria
positive
staphylococcus epidermidis shape
cocci, grapelike clusters
are staphylococcus epidermidis part of the normal flora? if so, where?
yes, skin and mucosa
staphylococcus epidermidis O2 requirements
facultative anaerobic
staphylococcus epidermidis virulence factors
catalase, exotoxins, exopolysaccharide slime, salt tolerance
which staphylococcus is an opportunistic pathogen?
staphylococcus epidermidis
staphylococcus saprophyticus is a gram __ bacteria
positive
is staphylococcus saprophyticus part of the normal flora? if so, where?
yes, Skin, genitourinary tract, mucous membranes
staphylococcus saprophyticus O2 requirements
facultative anaerobe
staphylococcus saprophyticus virulence factors
catalase, no known exotoxins, salt tolerant
what type of infections does staphylococcus saprophyticus cause?
UTIs in sexually active young females
staphylococcus saprophyticus shape
cocci, grapelike clusters
streptococcus pyogenes (GAS) is a gram __ bacteria
positive
streptococcus pyogenes shape
cocci, pairs or chains
is streptococcus pyogenes part of the normal flora? if so, where?
no
streptococcus pyogenes O2 requirements
faculative anaerobe
streptococcus pyogenes virulence factors
capsule, hyaluronidase, pyrogenic exotoxins/erythrogenictoxin, fibrinolysin, M protein, lipoteichoic acid
streptococcus pyogenes hemolysis
beta
what type of infections does streptococcus pyogenes cause?
acute pharyngitis, impetigo, cellulitis, necrotizing fasciitis, bacteremia, post-streptococcal disease
streptococcus agalactiae (group B) is a gram __ bacteria
positive
streptococcus agalactiae (group B) shape
cocci, pairs or chains
is streptococcus agalactiae (group B) part of normal flora? if so, where?
yes, vaginal tract and GI tract (5-30% of women)
streptococcus agalactiae (group B) O2 requirements
facultative anaerobe
streptococcus agalactiae (group B) virulence factors
capsule, other uncertain factors
what type of infections does streptococcus agalactiae (group B) cause?
multisystem infections in neonates, postpartum infections, immunocompromised individuals: bacteremia, pneumonia, endocarditis
enterococci (group D streptococci) is a gram __ bacteria
positive
is enterococci (group D streptococci) part of the normal flora? if so, where?
yes, GI tract, genitourinary tract in women
enterococci (group D streptococci) O2 requirements
facultative anaerobe
enterococci (group D streptococci) virulence factors
cytolysins, adhesions
what type of infections are caused by enterococci (group D streptococci)?
nosocomial infections (UTI, intra-abdominal)
what are the two common strains of enterococci?
E. faecium, E.faecalis
streptococcus pneumoniae (pneumococci) is a gram __ bacteria
positive
streptococcus pneumoniae (pneumococci) shape
cocci, pairs or chains
is streptococcus pneumoniae (pneumococci) part of the normal flora? if so, where?
yes, URT in 5-40% of women
streptococcus pneumoniae (pneumococci) O2 requirements
facultative anaerobe
streptococcus pneumoniae (pneumococci) virulence factors
capsule (polysaccharide), pneumolysin, IgA protease
streptococcus pneumoniae (pneumococci) hemolysis
alpha
viridans streptococcus is a gram __ bacteria
positive
viridans streptococcus shape
cocci, pairs or chains
is viridans streptococcus part of the normal flora? if so, where?
yes, oral cavity, GI, and female genitourinary tract
viridans streptococcus O2 requirements
facultative anaerobe
viridans streptococcus hemolysis
alpha and gamma
what type of streptococci is an opportunistic pathogen?
viridans streptococcus
viridans streptococcus virulence factors
extracellular complex polysaccharides
corynebacterium are gram __ bacteria
positive
corynebacterium shape
bacilli, clubbed/irregularly shaped
are corynebacterium part of the normal flora? if so, where?
yes (except C. diphtheria), mucous membranes of the skin, RT, UT, and conjunctiva
do corynebacterium form spores?
no
what type of infections do corynebacterium cause?
normally do not cause infections; EXCEPT C. diphtheria which is pathogenic and can cause an infection with symptoms: sore throat, fever, blockage of airways
listeria monocytogenes is a gram __ bacteria
positive
listeria monocytogenes shape
bacilli/coccobacilli
is listeria monocytogenes part of the normal flora? if so, where?
no
listeria monocytogenes virulence factors
catalase, listerolysin O, adhesions, proteins, internalins, ActA
is listeria monocytogenes spore forming?
no
is listeria monocytogenes motile?
yes
what type of infections does listeria monocytogenes cause?
variety in humans and animals, food poisoning (listerolysis)
lactobacillus are gram __ bacteria
positive
lactobacillus shape
bacilli
are lactobacillus part of the normal flora? if so, where?
yes, vaginal tract
bacilli are gram __ bacteria
positive
bacilli O2 requirements
aerobic and facultative aerobic
bacillus anthracis hemolysis
gamma
bacillus cereus hemolysis
beta
bacillus anthrax virulence factors
catalase, capsule, toxins
are bacillus anthrax spore forming?
yes
bacillus shape
bacilli, chains
what type of infections do bacillus cereus cause?
food poisoning
bacillus cereus virulence factors
catalase, enterotoxins, pyogenic toxins
is bacillus cereus motile?
yes
is bacillus cereus spore forming?
yes
what type of infections does bacillus anthracis cause?
disease of herbivores (contact with infected animal (products)), cutaneous, GI, or pulmonary anthrax
are clostridium part of the normal flora? if so where?
yes, intestinal tract
clostridium O2 requirements
anaerobic
do clostridium form spores?
yes
are clostridium motile?
yes
is escheria coli part of the normal flora? if so, where?
yes, GI tract, female genital tract
escheria coli O2 requirements
facultative anaerobic
escheria coli virulence factors
catalase, endotoxin
do escheria coli have pili?
yes
what type of infections do escheria coli cause?
UTI, bacteremia, neonatal meningitis, GI
are escheria coli oxidizers or fermenters?
fermenters
are shigella part of the normal flora? if so, where?
no
shigella O2 requirements
facultative anaerobe
shigella virulence factors
catalase (except dysenteriae), adhesion, invasion factors, intracellular spread and toxin production
what type of infections do shigella cause?
dysentery
are shigella oxidizers or fermenters?
fermenters
are salmonella oxidizers or fermenters?
fermenters
are salmonella part of the normal flora? if so, where?
usually no, sometimes bowel
salmonella O2 requirements
facultative anaerobe
salmonella virulence factors
catalase, adherence promoters, phagocytosis evaders, factors that dissemenate to other tissues
what type of infections do salmonella cause?
gastroenteritis, enteric fever, bacteremia
enterobacteriaeceae (shigella, E coli, salmonella) shape
short rods