PHA 329 MEDICAL CONDITIONS/EXOGENOUS TESTOSTERONE AND INFERTILITY

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Last updated 5:40 PM on 9/7/26
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4 Terms

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Hypogonadism

Reduced function of testes resulting in low testosterone

  • Primary: problem originates in testes; LH and FSH will be elevated

  • Secondary: problem originates in hypothalamus or pituitary; LH and FSH will be low-normal


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Erectile dysfunction

Inability to achieve or maintain erection

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Benign prostatic hyperplasia

non-cancerous growth of prostate gland resulting in urethral constriction

  • Associated with advanced age


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Exogenous Testosterone & Infertility

  • Exogenous testosterone decreases spermatogenesis due to negative feedback of HPG axis

    • Low GnRH, FSH, LH

  • Although serum testosterone increases, testosterone levels in testes are reduced

  • Typically results in oligospermia (low sperm count) or azoospermia (absence of sperm) and causes reversible male infertility