Chemical Agents That Affect the NMJ

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Last updated 2:18 PM on 10/15/26
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5 Terms

1
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How do organophosphates affect the NMJ?


They inhibit AChE, causing ACh to accumulate and potentially causing spastic paralysis

2
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How does black widow venom affect the NMJ?

It causes excessive ACh release and can cause spastic paralysis

3
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How does botulinum toxin affect the NMJ?

It blocks ACh release and can cause flaccid paralysis.

4
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What is spastic paralysis?

A condition involving excessive muscle contraction or stiffness.

5
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What is flaccid paralysis?

A condition involving loss of normal muscle tone and weakness