MIDTERM 2 PSYC 444 by Julia

memory consolidation in animals vs humans

in animals there is some evidence of neural replay during sleep

in humans memory activity can be decoded from EEG locked to slow oscillations spindle activity

four methods to study memory consolidation during sleep

observational - look for correlates(sleep stage %, sleep microarchitecture) after learning

sleep deprivation - or even select stage to deprive

targeted memory reactivation (TMR) - cues (sounds or odor) paired with learning are replayed during sleep 

closed loop acoustic stimulation -sounds timed to slow-wave UP states boost slow oscillations and memory

6 main models of sleep dependent memory

1. sleep protects memory from forgetting

2. REM sleep is for memory

3. sleep facilitates forgetting

4. dual process - REM sleep does one thing and SWS sleep does another 

5. sequential process -REM sleep does something first and then SWS does another afterwards 

6. active system consolidation - current accepted model

current framework (Brondt, 2023)

• sleep is a brain state that serves for memory consolidation

• replay of neuronal firing patterns is the basic triggers, in sleep and wake

• In SWS: