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What is the paracrine system?
A communication system that uses local mediators functioning in the immediate area around the releasing cell.
What types of molecules act as local mediators in the paracrine system?
Proteins, amino acid derivatives, and fatty acids.
What are prostaglandins?
Locally acting autocrine/paracrine lipid messenger molecules.
What are the physiological effects of prostaglandins?
Contraction and relaxation of smooth muscle.
Platelet aggregation.
Inflammation.
Fever.
Pain sensation.
What are growth factors and lymphokines in the paracrine system?
Growth factors: Local mediators involved in cell growth and repair.
Lymphokines: A subset of cytokines produced by T cells.