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Chapter 5 - Psychopharmacology and New Drug Development
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chemical name
label given to a drug that represents its structure
brand name
commercial label given to a drug by its manufacturer
generic name
general label given to a drug that is shorter and easier to say
initial sensitivity
effect of a drug on a first-time user
addictive personality
hypothesis of a character structure common to all people with substance use afflictions
drug expectancy
person’s belief about what he or she will experience upon taking a drug
dispositional tolerance
increase in the rate of metabolizing a drug as a result of its regular use
functional tolerance
decreased effects of a drug on demeanors as a result of regular use
acute tolerance
type of resistance that occurs within the course of action of a single drug dose
protracted tolerance
type of resistance that occurs over the course of two or more drug doses
behavioral tolerance
adjustment of demeanor through experience in using a drug to compensate for its intoxicating effects
cross-tolerance
resistance to a drug never taken that results from resistance to another drug
psychosis
severe mental condition whose symptoms include disorganized thinking and bizarre manner of conduct
attention deficit/hyperactivity disorder
condition with features such as a greater-than-normal amount of activity, restlessness, difficulty concentrating, and impulsivity
paradoxical
drug effect that is opposite in direction to what is anticipated based on its structure
reverse tolerance
increased receptivity to a drug with repeated use of it
homeostasis
state of equilibrium or balance
behavioral pharmacology
specialty area of drugs research that concentrates on drug use as learned action
reinforcer
consequence of an action that increases its future likelihood
punisher
consequence of an action that suppresses or decreases its future likelihood
self-administration study
research that involves testing whether participants will “give themselves” a drug
drug discrimination study
research procedure that primarily concerns the differentiation of drug effects
conflict paradigm
research procedure where the history of some action is followed by both reinforcement and punishment
generalizable
applicability of a research finding from one setting or group of research participants to another
causal relationship
connection between variables in which changes in one variable are due to changes in another
control group
reference or comparison group in an experiment
placebo control
type of comparison group originating in drug research
group design
type of experimental design in which groups of subjects are compared to establish experimental findings