histo- lymph node, spleen, MALT LOs

which type of CT proper provides structural scaffolding to the lymphocytes within the lymph node? what do they secrete?

reticular CT, secretes type III collagen fibers

what type of lymphocytes predominates in the nodular cortex?

B-lymphocytes

what type of lymphocytes predominates in the diffuse paracortex?

t-lymphocytes

between the germinal center and mantle of a secondary lymphoid nodule, which has proliferating b lymphocytes that are clonally dividing in response to antigenic stimulation?

germinal center

between the medullary cord and medullary sinuses, which is more densely populated with lymphocytes, plasma cells, and macrophages?

medullary cords

where is the subcapsular sinus?

deep to the capsule

where is the cortical sinus?

connects the subcapsular sinuses to medullary sinus

where is the medullary sinus?

medulla

what is the basic flow of the lymph through a lymph node beginnng with the vessels that deliver lymph and ending with the vessels that drain the lymph?

afferent lymphatic, subcapsular sinus, cortical sinus, medullary sinus, efferent lymphatic

what are the 2 ways the lymphocytes are delivered to a lymph node?

high endothelial venules (HEVs), afferent lymphatics

is smooth muscle present in the stromal structures: capsule and trabeulae?

yes in varying amounts

what is PALS? is it located in the white or red pulp?

periarterial lymphatic sheath, white pulp

white pulp

both diffuse and nodular lymphoid tissue

red pulp

both splenic sinuses and splenic cords

what is the marginal zone?

located between white and red pulp; site of antigen trapping

what type of CT proper provides the scaffolding to the red blood cells and lymphocytes within the spleen (both red and white pulp)?

reticular CT, secretes type III collagen

within the white pulp, which type of lymphocyte is predominant in the diffuse lymphoid tissue (surrounding central arteries)?

t-lymphocytes

within the white pulp, which type of lymphocyte is predominant in the nodular lymphoid tissue (in the margins of PALS)?

b-lymphocytes

between the splenic cords and splenic sinuses which direction to the RBCs move during the filtering process that removes senescent RBCs?

cords to sinuses

the spleen recieves the blood that is delivered to the organ, then subdivides the labor between the two pulps. which pulp functions like a lymph node and processes foreign antigens?

white pulp

the spleen recieves the blood that is delivered to the organ, then subdivides the labor between the two pulps. which pulp functions to capture and recycle old RBCs?

red pulp

what general category are tonsils under?

MALT (mucosa-associated lymphoid tissue)

what is a tonsil?

aggregates of lymphoid nodules in the pharynx

what is BALT?

bronchus/bronchiole associated lymphoid tissue); aggregates of nodular and diffues lymphoid nodules in the bronchi and bronchioles

what is GALT?

gut-associated lymphoid tissue; aggregates of diffuse and nodular lymphoid tissue in the GI tube