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Perichondrium
like a corset for cartilage, supports and protects
Dense CT, some vascularity
Hyaline cartilage
Surface of bones and joints, costal cartilage, tip of nose
Reduces friction, absorbs shock, provides structural support
Elastic cartilage
Similar to hyaline cartilage, but has more elastic fibers for flexible suppor
Fibrocartilage
More fibers for stronger support
Appositional growth
Building cartilage on top of existing cartilage
Pushing perichondrium further away
Interstitial growth
Growth within tissue
Functions of bone tissue
Support and protection
Movement
Reservoir for minerals and growth factors
Site of blood cell formation
Triglyceride storage
Hormone production
Bone classification
By location (Axial/Appendicular)
By shape (Long, short, flat, irregular)
Periosteum
Resilient membrane on outside of bone
Has a fibrous layer and an osteogenic (bone-creating) layer
Nutrient foramen for blood vessels
Endosteum
Inner membrane of bone
Also has osteogenic cells
Diploe
Spongy bone in a non-long bone
Bone marrow types
Yellow for fat storage, usually in adults
Red for blood cell formation, usually in children/teens
Adult bone marrow can become red if activity level increases drastically
Osteogenic cells
Stem cells
Actively mitotic
Daughter cells can differentiate
Osteoblast
build bone tissue
Secrete osteoid?
90% collagen fibers as well as Calcium binding proteins
Actively mitotic
May build themselves into lacunae
Osteocyte
Bone maintaining cell
Has projections for communication purposes
Bone-lining cells
Flatter, on external and internal surfaces
Help maintain bone matrix
Periosteal and endosteal cells
Osteoclast
does not come from osteogenic cell, comes from macrophage
Large and multinucleate
Function is bone resorption (breakdown)
Ruffled border increases surface area for enzymes to degrade bone
Osteon
Structural unit of compact bone
Pillars that run parallel to bone
Lamellae
Layers of osteon
Function of collagen fibers in osteon
Give bone resistance to force in all directions
Central canals
Center of osteon, site of nerves and blood supply
Perforating canals
Allow central nerves and blood supply to reach all of the osteons in the bone
Canaliculi
Projections from osteocyte/lacunae to allow for communication
Circumferential lamellae
Layers around bone that don’t line up with osteons
Interstitial lamellae
between osteons
Provide structure/support
Trabeculae
Structural support of spongy bone
Organized along stress patterns to resist stress
Organic composition of bone
Osteogenic cells, osteoblasts, osteocytes, bone-lining cells, osteoclasts
Osteoid
Sacrificial bonds
Sacrificial bonds
Collagen fibers will break in order to prevent the whole bone from breaking
Inorganic composition of bone
Hydroxyapatites: Provide hardness and resistance to compression
Endochondral ossification
Inside cartilage; long bones
Intramembranous ossification
Bone is developing from a fibrous membrane
Resting zone
Closest to epiphyseal plate
Not much happening