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a group of organelles and molecules working together; fundamental unit of life
cell
two categories of cell
prokaryotes, eukaryotes
maintains water balance; allows organisms to control their internal solute composition/water potential
osmoregulation
diffusion of water across a semipermeable membrane from high to low water concentration
osmosis
water moving into the cell means the solution is ___
hypotonic
no net water movement means the solution is ___
isotonic
water moving out of the cell means the solution is ___
hypertonic
describe how much solute is dissolved in the solvent
tonicity
animal cells are ___ and plant cells are ___ in hypertonic tonicity
shriveled, plasmolyzed
animal cells are ___ and plant cells are ___ in hypotonic tonicity
lysed, turgid
why is turgid good for plants
plant cells have turgor pressure; even if water continues to flow in, the cell membrane pushes against the cell wall, causing turgor pressure; this makes the cell stay firm and stable, and plant cells love to be firm
best tonicity for plant cells
hypotonic
best tonicity for animal cells
isotonic
animal cells are ___ and plant cells are ___ in isotonic tonicity
normal, flaccid
water moves from ___ to ___ water potential
high, low
water moves from ___ to ___ concentration of water
high, low
water moves from ___ to ___ concentration of solute
low, high
water moves from ___ to ___ osmolarity
low, high
water is stored in ___ in plants
large vacuole
the pressure the water exerts back on the cell wall
turgor pressure
(plant cells) water has to move through
cell wall and cell membrane
cells take in molecules into the intracellular space; require ATP energy
endocytosis
the state in which net movement is zero by matching rates of water moving in and out of the cell
dynamic equilibrium
measures the tendency of water to leave one place in favor of another
water potential
net movement of molecules that require a channel protein to occur
facilitated diffusion
two forms of active transport
endocytosis, exocytosis
cells take in molecules into the extracellular space; require ATP energy
exocytosis
water potential is affected by the addition of
solutes and physical pressure
equation of water potential
water potential = pressure potential (0) + solute potential
equation of solute potential
solute potential = -iCRT
net movement of molecules with the concentration gradient; does not require ATP energy
passive transport
net movement of molecules against the concentration gradient; requires ATP energy
active transport
net movement of small, nonpolar molecules without aid of protein
diffusion
high surface area
more places for materials to enter/exit
why do cells need a large surface area to volume ratio?
to be efficient at transport
projections (like villi) will ___ the surface area to volume ratio
increase
cells with projections will be ___ efficient at transporting materials compared to other cell shapes
more
cells have to be big enough to ___
fit all the dna and molecules
cells have to be small enough to ___
efficiently exchange nutrients, oxygen, and waste with extracellular environments to maintain homeostasis
requires formation of a vesicle for bulk export of substances (endocytosis/exocytosis)
exocytosis
requires formation for bulk import of substances (endocytosis/exocytosis)
endocytosis
separation of charge across the membrane
membrane potential
examples of facilitated transport
facilitated diffusion, active transport
___ molecules require the facilitation of channel proteins
large, polar, and charged
examples of passive transport
diffusion, facilitated diffusion, osmosis
The difference in concentration of molecules across a space
concentration gradient
importance of cell transport
transport waste out, absorption of nutrients, oxygen in for respiration, maintain homeostasis
membrane only lets small, non-polar molecules diffuse freely through the spaces between the phospholipids
selective permeability
how do integral proteins stay embedded within membrane?
nonpolar amino acids; anchors protein into membrane
how do integral proteins stay embedded on outer surfaces of membrane?
polar amino acids; extend into extracellular fluid and cytosol
transmembrane proteins with a channel through the middle; used for transport of large, polar, or charged molecules
channel proteins
transmembrane or peripheral proteins that do not have a channel through the middle; used for cell-signaling (ligands bind to the receptor and cause cell to respond)
receptor proteins
functions of cell membrane proteins
transporter, enzyme activity, cell surface receptor, cell surface identity marker, cell adhesion, attachment to cytoskeleton
regulates membrane fluidity in response to temperature changes
cholesterol
carbohydrates attached to phospholipids; facilitate cell-to-cell adhesion and recognition
glycolipids
carbohydrates attached to phospholipid proteins; allow cross linking of cells, which give tissues strength
glycoproteins
membrane without cholesterol
(cold-no flexibility, may break) (hot-too flexible, won’t hold shape)
responsible for controlling what enters and exits the cell; lipid membrane; mainly composed of phospholipids
cell membrane
site of ribosome synthesis in the cell
nucleolus
entire region between the nucleus and the cell membrane; consists of cytosol
cytoskeleton
contains nucleolus and chromatin; site of transcription (DNA transcribed into mRNA)
nucleus
consists of DNA and protein; condenses to form chromosomes
chromatin
double membrane that forms boundary between nuclear contents and cytoplasm; perforated with pores; surrounds nucleus
nuclear envelope
site of protein synthesis (suspended in the cytosol; produces protein for use within cell)
ribosomes (free)
site of protein synthesis (attached to the outside surface of ER; produces proteins for use outside cell or for cell membrane)
ribosomes (bound)
synthesizes lipids/hormones; detoxification of cell waste; doesn’t have attached ribosomes
smooth er
flattened membranous sacs; receives transport vesicles from ER; modifies ER products;
produces lysosomes and secretory vesicles
golgi apparatus
channels proteins to transport vesicles; attaches carbohydrate to some proteins;
involved in membrane production through production of vesicles; has attached ribosomes
rough er
carries ER products to golgi apparatus
transport vesicle
carries golgi apparatus products to cell membrane; fuses with cell membrane releasing contents outside the cell
secretory vesicle
membrane found sac of hydrolytic enzymes; enzymes used to digest food
lysosomes
membrane bound sacs; larger than vesicles; stores materials
vacuole
site of cellular respiration; produces ATP from sugars, fats, etc.
mitochondria
site of photosynthesis; produce food using light energy, CO2 and H2O
choloroplast
contains enzymes that transfer H from substrates to oxygen producing H2O2; detoxifies alcohol
peroxisome
paired structures found in animal cells; involved in cell division
centrioles
maintain the shape of animal cells; help vesicles get transported
cytoskeleton
as cells get bigger, its volume increases ___ than its surface area
faster
smaller objects have a ___ ratio of surface area to volume
greater
cell theory
all living things are made up, fundamental unit, comes from preexisting cells
endosymbiotic theory
eukaryotes evolved from prokaryotes
usually folded to increase surface area
organelle membranes
more specialization =
more complex life
organelles that do not have their own membrane inside of cell
non-membrane bound organelles (ribosomes, cell membrane, cell wall, cytoplasm)
organelles that have their own membrane inside of cell
membrane bound organelles (nucleus, vacuole, mitochondria, choloplast, golgi apparatus, er)
bacteria/archaea; single celled; no nucleus; no membrane bound organelles; older; smaller/simpler
prokaryotes
plants/animals/fungi/protists; single or multi cell; nucleus; membrane bound organelles; larger/complex; evolved;
eukaryotes
in ___, cell takes in macromolecules and particulate matter by forming new vesicles derived from the plasma membrane
endocytosis
cell engulfs solid material; fuses with lysosome for digestion
phagocytosis
cell engulfs dissolved particles; non-specific process
pinocytosis
triggered by molecular signal
receptor-mediated endocytosis
three types of endocytosis
phagocytosis, pinocytosis, receptor-mediated endocytosis