GNK MOD1, infectie en klinische presentatie

Staphylococcus aureus

Huidinfecties, sepsis, artritis, toxisch shock syndroom

Staphylococcus epidermidis

Katheter/prothese-infecties : Hospital-associated infectie

Streptococcus pyogenes

Tonsillitis, erysipelas, sepsis : sore throat

Streptococcus pneumoniae

Pneumonie, otitis, meningitis : cough, dyspnea, pleuritic. chest pain

Haemophilus influenzae

Otitis, meningitis, luchtweg : sore throat, swelling in the neck/stridor

Mycobacterium tuberculosis

Long-tuberculose, nachtzweten, gewichtsverlies

Neisseria meningitidis

Meningitis, sepsis, petechiën

Neisseria gonorrhoeae

Urethritis, cervicitis, PID (pelvic inflammatory disease)

Escherichia coli

UWI, sepsis, meningitis, diarree : dysuria/oliguria, flank pain

Salmonella enterica

Enteritis (diarree, koorts) : abdominal cramps, vomiting

Vibrio cholerae

Waterige diarree (rijstwater)

Campylobacter jejuni

Enteritis, diarree, koorts

Bacteroides fragilis

Intra-abdominale abcessen : abdominal pain, fever --> peritonitis

Clostridium difficile

Pseudomembraneuze colitis : diarree, abdominal cramping, toxic megacolon

Clostridium tetani

Tetanus : spasmen, kaakklem, respiratory failure

Borellia burgdorferi

Lyme : erythema migrans, artritis, meningitis, neurological symptoms

Treponema pallidum

Syfilis : ulcus, rash, neurosyfilis

Mycoplasma pneumoniae

Atypische pneumonie : milde koorts, cough, headache, pharyngitis with fever, sore throat

Chlamydia trachomatis

Urethritis, PID, trachoom (oogbindvliesontsteking)

Coxiella burnetii

Q-koorts : pneumonie, hepatitis, endocarditis

Legionella pneumophila

Legionellose (pneumonie) : dry cough, myalgia and headache

Influenza virus

Acute koorts, hoest, spierpijn, pneumonie

HIV

Aids: opportunistische infecties, gewichtsverlies

Enterovirussen (polio)

Poliomyelitis: asymptomatisch tot verlamming

Mazelenvirus

Koorts, exantheem, conjunctivitis, encefalitis

Herpes Simplex Virus

Koortslip, genitale herpes, encefalitis

Varicella Zoster Virus

Waterpokken, gordelroos

Cytomegalovirus (CMV)

Congenitaal, pneumonie, retinitis

Epstein-Barr virus (EBV)

Mononucleosis, lymfoom

Hepatits B Virus (HBV)

Acute/chronische hepatitis, HCC : jaundice (geelzucht), darkening of the urine

RS-virus (respiratoir syncytieel virus)

Bronchiolitis, pneumonie bij kinderen

SARS-CoV-2

Covid-19: koorts, hoest, dyspneu, trombose

Candida albicans

Spruw/thrush, vaginitis, sepsis

Aspergillus fumigatus

Invasieve aspergillose, allergische bronchopulm

Trichophyton mentagrophytes

Dermatofytose: ringworm, tinea pedis

Entamoeba histolytica

Dysenterie, leverabces

Toxoplasma gondii

Asymptotisch, encefalitis, congenitaal

Plasmodium vivax

Malaria tertiana (48u koorts) : hypotensie, splenomegaly, anemie

Plasmodium falciparum

Malaria tropica, cerebraal : hypotensie, splenomegaly, anemie

Giardia lamblia

Diarree, malabsorptie

Schistosoma haematobium

Hematurie, blaasfibrose

Schistosoma mansoni

Darm/leverfibrose

Strongyloides stercoralis

Diarree, huidlaesies, hyperinfectie

Taenia saginata

Lintworm, GI-klachten : diarree en gewichtsverlies

Hookworm (Necator, Ancylostoma)

Anemie, huidlaesies