Beta Oxidation enzymes and reactants

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Last updated 1:31 PM on 9/10/26
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21 Terms

1
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Step 1: Activation

- Fatty AcylCoA Synthetase
-ATP + CoASH -> AMP
- (-2 ATP)

2
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Step 2: Dehydration

- AcylCoA DH
- FAD -> FADH2
- (+1.5 ATP)

3
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Step 3: Hydroxylation

- Enoyl-CoA Hydratase
- H2O ->

4
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Step 4: Dehydration

- Beta Hydroxyacyl CoA DH
- NAD+ -> NADH
- (+2.5 ATP)

5
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Step 4: Cutting

- Thiolase
- CoASH->
- (+10 ATP)

6
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Step 1: CO2 Addition (odd) already activated

- Propinoyl Carboxylase
- Biotin
- HCO3- + ATP -> ADP + Pi
- (-1 ATP)

7
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Step 2: D->L (odd)

- Methylmalony CoA Epimerase

8
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Step 3: Formation of Succinyl CoA (odd)

- Methylmalony CoA Mutase
- Vitamin B12

9
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Step 4: Profit (odd)

- (+5 ATP) in Krebs
- (1 from GDP, 1.5 from FADH2, 2.5 from NADH+)

10
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Step 1: Moving the Double Bond (C3=C4) already activated

- Δ3, Δ2 Enoyl CoA Isomerase

11
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Step 2: Hydroxylation (C3=C4)

- Enoyl-CoA Hydratase
- H2O ->

12
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Step 3: Dehydration (C3=C4)

- Beta Hydroxyacyl CoA DH
- NAD+ -> NADH
- (+2.5 ATP)

13
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Step 4: Cutting (C3=C4)

- Thiolase
- CoASH->

14
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Step 1: Dehydration (C4=C5 cis)

- AcylCoA DH
- FAD->FADH2
- (+1.5 ATP)

15
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Step 2: "Merging" the Double Bond (C4=C5 cis)

- 2,4 Dienoyl CoA Reductase
- NADPH -> NADP
- (-2.5 ATP)

16
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Step 3: Moving the double bond (C4=C5 cis)

- Δ3, Δ2 Enoyl CoA Isomerase

17
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Step 4: Hydroxylation (C4=C5 cis)

- Enoyl-CoA Hydratase
- H2O->

18
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Step 5: Dehydration (C4=C5 cis)

- Beta Hydroxyacyl DH
- NAD+ -> NADH
- (+2.5 ATP)

19
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Step 6: Cutting (C4=C5 cis)

- thiolase
- CoASH ->
- (+10 ATP)

20
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Step 1: Glycerol Backbone

- Glyverol Kinase
- Mg2+
- ATP->ADP
- (-1 ATP)

21
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Step 2: Glycerol Backbone

- Glycerol-3-Phosphate DH
- NAD+ -> NADH
- (+2.5 ATP)