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Somatic motor system
One neuron pathway targeting skeletal muscle. Cell bodies in ventral horn of grey matter. Purely stimulatory effects.
Autonomic motor system
Two-neuron pathway targeting smooth muscle, cardiac muscle, glands. Consists of preganglionic neuron and postganglionic neuron with stimulatory or inhibitory effects
Preganglionic axon length in symp vs para divisions
Symp: Short (myelinated), para: long (myelinated)
Postganglionic axon length in symp vs para divisions
Symp: Long (unmyelinated), para: short (unmyelinated)
Ganglia location in symp vs para divisons
Symp: close to spinal cord; para: close to or within target organ wall
Neurotransmitters in symp vs para divisions
Symp: Ach at ganglion, norepinephrine at target organ; para: Ach at both ganglion and target organ
Response type in symp vs para divisions
Symp: widespread; para: localized
CNS origin in symp vs para divisions
Symp: T1-L2 lateral horn of grey matter; para: Brainstem and sacral spinal cord
White rami communicantes
Contain myelinated preganglionic sympathetic axons (T1-L2)
Gray rami communicantes
Contain myelinated postganglionic sympathetic axons exiting back to spinal nerves
Foregut artery, ganglion, and plexus
Celiac trunk, celiac ganglion, celiac plexus
Midgut artery, ganglion, plexus
Superior mesenteric artery, superior mesenteric ganglion, superior mesenteric plexus
Hindgut artery, ganglion, and plexus
Inferior mesenteric artery, inferior mesenteric ganglion, inferior mesenteric plexus
Vagus nerve (CN X)
Primary cranial nerve providing parasympathetic innervation to thoracic and abdominal viscera up through midgut
Adrenal medulla innervation
Directly innervated by preganglionic sympathetic axons with no postganglionic neuron
Adrenal medulla pathway function
Activation causes secretion of epinephrine and norepinephrine directly to capillaries for systemic stress response
Autonomic plexus
Composed of sympathetic postganglionic axons, parasympathetic preganglionic axons, and visceral sensory axons that branch with arteries to target organs
Referred pain
Occurs when visceral sensory pain signals are perceived as originating from a skin dermatome rather than organ itself due to convergence in shared spinal cord segments
What organs are in foregut
Esophagus, stomach, liver, gallbladder, spleen, 1st and 2nd parts of duodenum
What supplies the foregut
Celiac trunk
What organs are found in the midgut
3rd and 4th part of duodenum, jejunum, ileum, cecum, appendix, ascending colon, 2/3 of transverse colon
What supplies the midgut
Superior mesenteric artery
What organs are found in the hindgut
Distal 1/3 of transverse colon, descending colon, sigmoid colon, rectum
What supplies the hindgut
Inferior mesenteric artery
What is superior 1/3 of esophagus made of
Skeletal muscle (voluntary control)
What is middle 1/3 of esophagus made of
Mix of skeletal and smooth muscle
What is inferior 1/3 of esophagus made of
Smooth muscle (involuntary control)
What is the superior esophageal sphincter
Sits at junction with pharynx (throat)
What is the inferior esophageal sphincter (cardiac sphincter)
Sits at esophageal hiatus of diaphragm to prevent stomach acid reflux
Stomach muscularis externa: 3 layers
All smooth muscle: innermost oblique layer, middle circular layer, outermost longitudinal layer
Parietal cell
Gastric cell that secretes HCl and intrinsic factor (vitamin B12 absorption)
Chief cell
Gastric cell that secrete pepsinogen and gastric lipase
Surface mucous cells
Gastric cell that secrete an alkaline fluid with mucin to protect lining from acid
Mucous neck cells
Gastric cell that secrete an acidic fluid with mucin
Enteroendocrine cell
Gastric cell that secrete the hormone gastrin into bloodstream
What is stomach innervated by
Autonomic innervation from celiac plexus
What is stomach supplied by
Celiac trunk
What are the regions of small intestine
Duodenum, jejunum, ileum
Which part of small intestine is primary site of chemical digestion/nutrient absorption
Jejunum
What parts of small intestine contribute to surface area adaptations
Circular folds, villi, microvilli
What crypt cells are in small intestine
Paneth cells, stem cells
What are paneth cells
They secrete antimicrobial peptides in small intestine
What ducts form the hepatopancreatic ampulla
Common bile duct and main pancreatic duct
What does the conducting portion of respiratory system consist of
Nose, nasal cavities, paranasal sinuses, pharynx, larynx, trachea, bronchi, and bronchioles
What is the function of the conducting portion of respiratory system
Conditions the air by filtering, warming, and humidifying it before it reaches the lungs
What does the respiratory portion of the respiratory system consist of
Respiratory bronchioles, alveolar ducts, alveoli
What is respiratory portion of respiratory system function
Serves as site of gas exchange between air and blood
What are the functions of respiratory system?
Breathing, gas exchange, gas conditioning, sound production and communication, olfaction, defense
What is the function of trachea
Acts as primary airway connecting larynx to bronchial tree while trapping and clearing debris
Primary bronchi
Bifurcate at carina, right main bronchus is wider, shorter, and more vertical than left
Secondary bronchi
3 in right lung, 2 in left lung
Tertiary bronchi
Supply distinct bronchopulmonary segments (10 in right, 8-10 in left)
Bronchioles
Small airways leading to terminal bronchioles
Pulmonary circuit (blood supply)
Pulmonary arteries carry deoxygenated blood from right ventricle to lungs, branching alongside bronchial tree to form capillary beds around alveoli for gas exchange. Oxygenated blood drains through pulmonary veins to left atrium.
Bronchial circulation (blood supply)
Bronchial arteries carry oxygenated blood directly to structural tissues of bronchial tree and visceral pleura. Venous blood drains into pulmonary veins.
Components of superior mediastinum
Thymus, great vessels, trachea, esophagus, vagus nerves, phrenic nerves
Components of anterior mediastinum
Space between sternum and pericardium containing loose CT, fat, lymphatic vessels, and internal thoracic vessel branches
Components of middle mediastinum
Heart, pericardium, roots of great vessels
Components of posterior mediastinum
Thoracic aorta, esophagus, thoracic duct, azygos venous system, vagus nerves, phrenic nerves, thoracic sympathetic trunk