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Prosthetic group
Molecule permanently associated with a protein and required for its function
Transient interactions
Ligand is a molecule that is bound reversibly by a protein
Induced fit
Structural adaptation between protein and ligand
Substrate
Molecule changed by an enzyme
Catalytic site or active site
Binds substrate and facilitates its chemical transformation
Non enzymatic protein regulation
Binding protein controls affinity
Controls their transport function