Chapter 12: The Nervous System, Neurons, and Glial Cells

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Comprehensive practice flashcards reviewing the anatomical and functional divisions of the nervous system, neuronal anatomy, and central and peripheral neuroglial cells from Chapter 12.

35 Terms

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Central Nervous System (CNS)

The anatomical division of the nervous system consisting of the brain located within the cranial cavity and the spinal cord located within the vertebral canal.

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Peripheral Nervous System (PNS)

The anatomical division encompassing all nervous tissue situated outside the brain and spinal cord, including cranial and spinal nerves.

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Gray Matter

Regions within the central nervous system composed primarily of localized collections of neuron cell bodies and dendrites.

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White Matter

Regions of nervous tissue dominated by myelinated axons, named for the whitish appearance of the lipid-rich myelin sheath.

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Nucleus (Nervous System)

A discrete localized collection or cluster of neuron cell bodies located specifically within the central nervous system.

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Tract

A bundle of axons or nerve fibers sharing a common origin and destination within the central nervous system, such as the optic tract.

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Ganglion

A knotlike swelling or cluster of neuron cell bodies situated within the peripheral nervous system.

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Nerve

A cordlike bundle of axons and associated connective tissues located in the peripheral nervous system, such as the optic nerve.

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Sensation

The primary nervous system function of detecting internal or external environmental stimuli that register a change from homeostatic conditions.

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Integration

The central processing function that combines incoming sensory stimuli with memories, learning, and emotional state to formulate an appropriate output.

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Response (Motor Function)

The generation and delivery of motor commands to effector organs (such as skeletal, smooth, or cardiac muscle, or glands) following integration.

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Somatic Nervous System (SNS)

The functional division of the nervous system responsible for conscious perception, voluntary motor commands targeting skeletal muscle, and somatic reflexes.

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Autonomic Nervous System (ANS)

The functional division responsible for involuntary, subconscious regulation of cardiac muscle, smooth muscle, and glands to maintain homeostasis.

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Sympathetic Division

A branch of the autonomic nervous system that prepares the body for physical exertion or emergency states, commonly termed the 'fight or flight' response.

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Parasympathetic Division

A branch of the autonomic nervous system responsible for energy conservation and restorative functions, commonly termed the 'rest and digest' response.

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Enteric Nervous System (ENS)

A specialized division of the peripheral nervous system embedded within the gastrointestinal tract that regulates digestive smooth muscle and secretions independently of the central nervous system.

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Neuron

An excitable cell specialized to receive, generate, and propagate electrical impulses to communicate with target cells.

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Soma (Cell Body)

The core metabolic center of a neuron that houses the nucleus and cytoplasmic organelles.

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Dendrite

A highly branched cytoplasmic process of a neuron that receives incoming chemical or physical stimuli and carries signals toward the soma.

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Axon

A single elongated process of a neuron that conducts outgoing nerve impulses away from the cell body toward target cells.

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Axon Hillock

The cone-shaped transition zone connecting the soma to the axon where outgoing action potentials typically originate.

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Axon Terminal

The branched distal ending of an axon terminating in synaptic end bulbs (knobs) that release neurotransmitters across synapses.

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Synapse

The functional junction where an axon terminal communicates with a target cell through the release of chemical signaling molecules called neurotransmitters.

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Neuroglia (Glial Cells)

Non-excitable supporting cells in the central and peripheral nervous systems that do not propagate impulses but physically and biochemically support neurons.

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Astrocyte

A star-shaped neuroglial cell in the CNS that regulates extracellular ion and chemical balances, cleanses excess neurotransmitters, repairs damaged tissue, and forms the blood-brain barrier.

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Blood-Brain Barrier (BBB)

A selective physiological barrier established by astrocyte foot processes and capillary endothelial tight junctions that limits the entry of bloodborne substances, drugs, and leukocytes into the CNS.

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Oligodendrocyte

A central nervous system glial cell with multiple cellular extensions that simultaneously insulates multiple axon segments with myelin.

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Microglia

Small, phagocytic neuroglial cells of the CNS derived from macrophage lineages that ingest cellular debris, necrotic tissue, and pathogens during injury or stroke.

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Ependymal Cell

An epithelial-like glial cell of the CNS that lines the brain ventricles and central canal, possessing apical cilia to circulate cerebrospinal fluid and participating in fluid filtration at choroid plexuses.

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Choroid Plexus

A specialized vascular structure located within brain ventricles where ependymal cells filter blood plasma to produce cerebrospinal fluid containing oxygen, glucose, vitamins, and ions.

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Satellite Cell

A glial cell of the peripheral nervous system that surrounds and electrically insulates neuron cell bodies within ganglia and regulates localized nutrient-waste exchange.

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Schwann Cell (Neurolemmocyte)

A peripheral nervous system glial cell that wraps around a single axon segment to produce a segment of the myelin sheath and neurilemma, speeding electrical propagation.

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Myelin Sheath

A multilayered, lipid-rich insulating sheath composed of plasma membrane phospholipids that wraps around axons to accelerate action potential conduction.

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Node of Ranvier

Unmyelinated gaps along an axon between adjacent Schwann cells or oligodendrocyte myelin segments that facilitate rapid nerve impulse transmission.

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Neurilemma

The outer nucleated cytoplasmic layer of a Schwann cell wrapping the outermost layer of the myelin sheath along peripheral axons.