folliculogenesis

folliculogenesis

the process of follicle development

where are follicles located in the ovary

in the cortex of the ovary

what do primordial germ cells become

Oogonia, which after divisions will enter meiosis

what stage of the oocyte arrest at

Primary oocyte in Meiosis 1

what is a primordial follicle

• primary oocyte

• surrounded by a few flattened follicular cells

what defines a primary follicle

continuous cuboidal follicular cells around the oocyte

what are key features of a secondary follicle

• multiple layers of follicular cells

• formation of theca layers

• beginning of small fluid cavities

what structure develops in the secondary follicle stage

zona pellucida (glycoprotein coat around oocyte)

in secondary follicle phase, what are follicular cells now called

granulosa cells

Tertiary follicle (antral/graafin) follicle

• large antrum (fluid-filled cavity)

• many granulosa cells

what are cumulus cells

granulosa cells surrounding the oocyte

what layers support the follicle

• theca interna and externa

what causes follicle rupture

• fluid build up + pressure

• breakdown of follicle wall

What is released during ovulation

secondary oocyte

what forms immediately after ovulation

corpus hemorrhagicum

what does the corpus hemorrhagicum become

corpus luteum

what hormone does the CL produce

progesterone

what is atresia

degeneration of follicles that don’t ovulate

when are all oocytes formed

before or shortly after birth

when is Meiosis I completed

just before ovulation

When is Meiosis II completed

after fertilization

Summarize folliculogenesis

Primordial → Primary → Secondary → Antral → Ovulation → Corpus luteum → Corpus albicans