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Gene pool
the sum of all alleles in a population. Take population size x 2 in order to calculate the gene pool. (we are diploid individuals which is why 2x)
Maladaptive
leading to lower fitness
Deleterious mutation
A mutation or other event that lowers fitness.
Inbreeding depression:
Reductions in the average fitness of individuals in a population, due to the increased prevalence of homozygous recessive genotypes that have deleterious effects.
Extinction vortex
In some genetically isolated populations, a self-reinforcing cycle that lowers fitness and population size.