botanical quiz review

For the Latin binomial name, Catharanthus roseus, indicate which part of the name represents the genus and species

Catharanthus - genus

roseus - species

list 2 types of healthcare systems

homeopathy and allopathy

Under the dietary supplement health and education act (DSHEA) who is responsible for ensuring the safety and proper labeling of products?

manufacturers

What are two ways the FDA monitors safety of supplements?

consumer complaint and post market adverse event formulary

What alkaloid dietary supplement formerly used for athletic performance, increased energy, and weight loss was banned in 2004 by the FDA?

ephedra

A semi purified fraction of polyphenolic catechins that has been approved by the FDA for the treatment of genital warts

camelia sinensis

it has been marketed for >200 years as a standardized botanical (contains over 30 cardiac glycosides as identified actives, including digoxin and digitoxin)

digitalis

the sap of a botanical that was approved by FDA in 2013 for symptomatic relief of non-infectious diarrhea in HIV/AIDS patients

croton lechleri

The role that pharmacists play in process of dietary supplements/herbal products is an important one. List 3 main aspects discussed in class that make up the role?

• drug interactions

• mechanism of action

• quality of drug and we have comprehensive information about it

define standardization for herbal drug preparation

adjustment of composition to make sure they’re consistent

in an observation study why is the data limited for demonstrating efficacy of a botanical treatment

lack of control variable, less variables measured

as a pharmacist (botanical specialist), discuss a questionable assumption in the use of dietary supplement

everything is safe and effective

why is standardization important for BDA

need to know the amount of active drug compounds and if there are adulterants

type of standardization presently learning in class

preclinical, biology, clinical

what includes preclinical standardization

chemistry, in vitro, and vivo (animals)

what are the differences between quality control and quality assurance

QC - products

QA -process related

camilia sinesis is an herbal product that has a variety of uses. discuss the uses, types of constituents, and the health benefits of this herbal product

• common uses of green tea: feel more awake, antimicrobial, anticancer, cardiovascular conditions, lipidemia

• approved for the treatment of genital warts

• active constituents: catechins

Sangre de Drago is a herbal product that has a variety of uses. Discuss these uses and the health benefits of this herbal product

• HIV induced diarrhea, atypical use for miscarriage

• active compounds: alkaloids, terpenes, flavonoids