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spinal nerves
______ consits of
axon bundles
Schwann cells
connective tissue (3 types of CT)
Endoneurium
type of connective tissue in spinal nerves that surrouds individual neurons
Perineurium
type of connective tissue in spinal nerves that surrounds axon groups to form fascicles
Epineurium
type of connective tissue in spinal nerves that surrounds the entire nerve
first
the _____ pair of spinal nerves exit the vertebral column between the skull and atlas
exit
the last 4 pairs of spinal nerves ____ via the sacral foramina

intervertebral
the rest of the spinal nerves (excluding the first and last 4) exit through the _______ foramina

Dermatomal Map
skin area supplied with sensory innervation by spinal nerves
spinal nerves indicated by capital letter and number (C1)
important because they can be used to help locate nerve damage
Rami
another word for BRANCHES of spinal nerves
Dorsal Ramus
innervate deep muscles of the trunk responsible for movements of the vertebral column and the CT and skin near the midline of the back
Ventral Ramus
what they innervate depends upon which part of the spinal cord is considered
these wrap to the front of the body
consists of the thoracic region and form 5 plexuses
thoracic region
the _____ is part of the ventral ramus that form intercoastal nerves that innervate the intercoastal muscles and the skin over the thorax
also form nerve plexuses
roots of the plexus
remaining spinal nerves in the ventral rami (_______) after the thoracic region is considered: form 5 plexuses (intermingling of nerves)
cervical plexus- C1-C4
brachial plexus- C5-T1
lumbar plexus- L1-L4
sacral plexus- L4-S4
coccygeal plexus- S5
C1
the only spinal nerve that doesn’t have a specific cutaneous sensory distribution
Cutaneous Sensory Innervation
where the specific nerves fuel the skin. For example, if you touch someone’s foot sole, they feel it because the tibial nerve supplies that area of skin
Communicating Rami
branch that communicates with sympathetic chain of ganglia
Cervical Plexus
C1-C4
innervates superficial neck structures, skin of neck, and posterior portion of the head
Ansa Cervicalis: loop between C1 and C3 that serves the infrathyroid muscles
has the Phrenic nerve
ansa cervicalis
loop between C1 and C3 that serves the infrathyroid muscles
Phrenic nerve
from C3-C5 (cervical and brachial plexuses)
innervates diaphragm
Brachial Plexus
originates from C5-T1
five ventral rami form 3 trunks that separate into 6 divisions then form cords that give rise to 5 branches/nerves
Branches of the Brachial Plexus
Axillary nerve
Radial nerve
Musculocutaneous nerve
Ulnar nerve
Median nerve
Axillary nerve
origin: posterior cord of brachial plexus C5-C6
movements: laterally rotates arm, and abducts arm
cutaneous (sensory) innervation: inferior lateral shoulder
radial nerve origin
origin is the posterior cord of the brachial plexus C5-T1
radial nerve movements
extends and flexes elbow
extends, adducts, and abducts wrist
supinates forearm and hand
extends fingers
abducts and extends thumb
cutaneous innervation: posterior surface of arm and forearm; lateral 2/3rds of dorsum of hand
Musculocutaneous nerve origin
originates in lateral cord of brachial plexus, C5-C7
Musculocutaneous nerve movements
flexes shoulder
flexes elbow
supinates forearm and hand
Cutaneous innervation: lateral surface of the forearm
Ulnar nerve origin
origin: medial cord of brachial plexus; C8-T1
Ulnar nerve movements
flexes and adducts wrist
flexes, abducts, and adducts fingers
adducts thumb
controls hypothenar muscles
flexes metacarpophalangeal joints and extends interphalangeal joints
Cutaneous innervation: medial third of hand, little finger, and medial half of ring finger
median nerve origin
origin: medial and lateral cords of brachial plexus; C5-T1
median nerve movements
pronates forearm and hand
flexes and abducts wrist
flexes fingers
controls thumb and thenar muscles
flexes metacarpophalangeal joints and extends interphalangeal joints
median nerve cutaneous innervation
lateral two-thirds of palm and hand, thumb, index and middle fingers, and the lateral half of the ring ringer and dorsal tips of the same fingers
innervates all but 1 flexor muscle
Lumbar and Sacral Plexus
lumbar plexus: ventral rami of L1-L4
sacral plexus: ventral rami of L4-S4
usually considered together because of their close relationship
4 major nerves: Obturator, femoral, tibial, common fibular
Obturator nerve origin
lumbosacral plexus; L2-L4
Obturator nerve movements
rotates thigh laterally
adducts thigh
adducts thigh and flexes knee
cutaneous innervation: superior medial side of the thigh
Femoral Nerve origin
lumbosacral nerve; L2-L4
(not the obturator one)
femoral nerve movements
flexes hip
flexes hip and flexes knee
extends knee and flexes hip
Cutaneous innervation: anterior and lateral branches supply the anterior and lateral thigh; saphenous branch supplies the medial leg and foot
innervates iliopsoas and sartorius muscles
Tibial and Common Fibular Nerves
called the peroneal nerves.
together they’re referred to as the sciatic (ischiadic) nerve since they are bound together within the same sheath of the thigh
Tibial Nerve
Origin: lumbosacral plexus; L4-S3
Movements:
extends hip and flexes knee
extends hip and adducts thigh
plantar flexes foot
flexes knee
flexes toe
Cutaneous innervation: none
Additional info of tibial nerve
it also innervates the posterior portion of the thigh, leg, and foot
ex: used when dancer points toes (flexes toe movement)
Medial and Lateral Plantar Nerves of Tibial Nerve
origin: tibial nerve
movement: flex and adducts toe
cutaneous (sensory) innervation: sole of the foot
Sural nerve of Tibial nerve
origin: tibial nerve
movement/muscle innervation: none
cutaneous (sensory) innervation: lateral and posterior 1/3rd of the leg and lateral side of the foot
Fibular Nerve Areas
common fibular (peroneal) nerve
deep fibular (peroneal) nerve
superficial fibular (peroneal) nerve
Common fibular nerve
origin: lumbosacral plexus; L4-S2
movement/muscle innervation: extends hip and flexes knee
cutaneous innervation: lateral surface of the knee
ex: innervates anterior and lateral muscles of the leg and foot, skin of anterior and lateral leg and dorsum of the foot
Deep Fibular Nerve
origin: common fibula (peroneal) nerve
movement: dorsiflexes and extends foot
cutaneous innervation: great and second toe
Superficial Fibular Nerve
origin: common fibular nerve
movement: plantar flexes and everts foot
cutaneous innervation: dorsal anterior third of the leg and dorsum of the foot
Coccygeal Plexus
S5
muscles of the pelvic floor
sensory information from the skin over the coccyx
Spinal stenosis
Narrowing of spinal canal or area around nerve roots; leads to compression of
nerves; usually cervical (neck) or lumbar (lower back); can cause pain, numbness, or
weakness
Encephalitis
Inflammation of the brain caused by a virus and less often by bacteria or other
agents; symptoms include fever, coma, and convulsions
Meningitis
Inflammation of meninges caused by viral or bacterial infection; symptoms include
stiffness in the neck, headache, and fever; severe cases can cause paralysis, coma,
or death
Rabies
Viral disease transmitted by an infected animal; brain infection results in abnormal
excitability, aggression, paralysis, and death
Tetanus
Caused by bacterial neurotoxin; affects lower motor neurons in spinal cord and
brainstem, leading to muscle contraction; prevents muscle relaxation; body becomes
rigid, including “lockjaw”; death results from spasms in respiratory muscles
Multiple sclerosis
Autoimmune condition; may be initiated by viral infection; inflammation in brain and
spinal cord with demyelination and sclerotic (hard) sheaths results in poor conduction
of action potentials; symptoms include exaggerated reflexes, tremor, and speech
defects
Anesthesia
Loss of sensation; may be a pathological condition or may be induced temporarily to facilitate medical action
Neuritis
inflammation of a nerve from a number of causes; in motor nerves, can result in loss of motor function; in sensory nerves, can result in anesthesia or neuralgia
Neuralgia
Nerve pain; involves severe spasms of throbbing or stabbing pain along the pathway of a nerve; can result from inflammation, nerve damage, or an unknown cause
Sciatica
Neuralgia of the sciatic nerve, with pain radiating down the back of the leg; most common cause is a herniated lumbar disk
Leprosy
Bacterial disease that kills skin and PNS cells; characterized by disfiguring nodules and tissue necrosis
Herpes
Family of diseases characterized by skin lesions due to herpes viruses in sensory ganglia; different viruses cause oral lesions (cold sores), sexually transmitted disease with lesions on genitalia, or chickenpox in children (shingles in adults)
Poliomyelitis
Viral infection of the CNS, but primarily damages somatic motor neurons, leaving muscles without innervation; leads to paralysis and atrophy
Diabetic neuropathy
Damage to nerves occurs in diabetic patients due to high blood sugar levels and decreased blood flow; occurs in over half of diabetics; symptoms develop slowly, often including pain or numbness in extremities but can be manifested in every organ system
Charcot-Marie-Tooth disease
One of the most common hereditary neurological disorders (named for three neurologists who described it); different forms caused by mutations that generally lead to damage of the myelin sheath; characterized primarily by muscle weakness, dysfunction, atrophy, and loss of sensation primarily in lower extremities
Neurofibromatosis
Genetic disorder; neurofibromas (benign tumors along peripheral nerve tract) occur in early childhood and result in skin growths
Myasthenia gravis
Autoimmune disorder affecting acetylcholine receptors; makes the neuromuscular junction less functional; muscle weakness and increased fatigue lead to paralysis