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• Intermittent apnea / bradycardia
• Infant Respiratory Distress Syndrome / Hyaline Membrane Disease (HMD)
Related to Prematurity
• BPD
related to LT (+) pressure ventilation
• Meconium Aspiration Syndrome
• Transient Tachypnea of Newborn (TTNB)
Occurring at Birth
• SIDS
Occurring After Birth
• Cystic Fibrosis
Congenital
Apnea of Prematurity are transient periods of
apnea that last 15-20 sec
typically accompanied by bradycardia
What is the most common respiratory disorder of premature infants born under 37 weeks GA?
Hyaline Membrane Disease (HMD)
Neonatal or Infant Respiratory Distress Syn (NRDS / IRDS)
The etiology of Hyaline Membrane Disease / Neonatal or Infant Respiratory Distress Syndrome involves
Inadequate surfactant production + lung immaturity
→ hypoxemia due to lack of gas exchange
Bronchopulmonary Dysplasia (BPD) is linked to long term
positive pressure ventilation and O2 therapy
Bronchopulmonary Dysplasia (BPD) may be associated with
CP outcome or neurological sequlae
Bronchopulmonary Dysplasia (BPD) may progress to s/s consistent with
chronic restrictive lung disease
s/s consistent with chronic restrictive lung disease include all of the followig EXCEPT
Decreased incidence of respiratory infection
Meconium Aspiration Syndrome involves infants that aspirates mixature of
meconium (contents of bowels) + amniotic fluid
Meconium Aspiration Syndrome occurs within
first few postnatal breaths
Meconium Aspiration Syndrome may cause
airway obstruction and atelectasis
Meconium Aspiration Syndrome puts infant at tisk for
tension pneumothorax, pulm HTN, bronchiolitis and pneumonitis
Transient Tachypnea of Newborn (TTNB) is respiratory distress caused by
delayed clearance of fetal lung fluid
Transient Tachypnea of Newborn (TTNB) usually corrects with
little more than observation (self limiting)
Sudden Infant Death Syndrome =
Unexplained death of an infant < 1 year of age
Possible etiologies inckude all of the following EXCEPT
Back to Sleep Campaign – started in 1994 has
dramatically reduced incidence
Cystic Fibrosis is a(n)
autosomal-recessive disease affecting exocrine gland function
90% of CF related deaths are due to
pulmonary compromise
How can PTs play an important role in cystic fibrosus?
• Postural Drainage • Airway clearance • Rib cage mobility • Postural training • General exercise
A complete diagnostic evaluation of cyctic fibrosus should include all of the following EXCEPT
Family genetic testing
What is screened for newborns suspected of having cystic fibrosis?
Levels of of Immunoreactive Trypsinogen (IRT)
Increased levels of Immunoreactive Trypsinogen are seen in
preemies
stressful deliveries
infants or carriers of CF
(if + = more tests)
Chest PT for Airway Clearance should start in
Infancy (12 locations- 2 min each)
What is no longer recommend for airway clearance?
head down