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Resting membrane potential
Inside is negative; K+ leaks out
Na+/K+ pump
Uses ATP to move 3 Na+ out and 2 K+ in
Action potential
Na+ enters to depolarize; K+ exits to repolarize
All-or-none principle
An action potential happens fully or not at all
Refractory periods
Absolute: cannot fire again. Relative: needs a stronger stimulus
Myelin
Speeds signals; action potentials renew at nodes of Ranvier
Electrical vs. chemical synapse
Electrical: direct ion flow. Chemical: neurotransmitter release
Excitatory vs. inhibitory
Excitatory promotes depolarization; inhibitory promotes hyperpolarization
Neurotransmitter release
Ca2+ enters the terminal, triggering vesicle fusion
Neurotransmitter removal
Reuptake or breakdown; acetylcholinesterase breaks down acetylcholine