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oppositional defiant disorder, intermittent explosive disorder, conduct disorder
what are the 3 disruptive, impulse control, and conduct disorders that are discussed?
oppositional defiant disorder
frequent and persistent pattern of angry and irritable mood, argumentative, defiant behavior, and vindictiveness
oppositional defiant disorder
what conduct disorder is more frequently confined to one setting (usually home)?
true
true or false: individuals with oppositional defiant disorder do not regard themselves as angry, oppositional, or defiant
males
which gender is oppositional defiant disorder more common in?
first symptoms around preschool and rarely later than adolescence
what is the symptom course for oppositional defiant disorder?
oppositional defiant disorder
what disorder often precedes the development of conduct disorder?
temperamental factors
oppositional defiant disorder factors: high levels of emotional reactivity, poor frustration tolerance
environmental factors
oppositional defiant disorder factors: harsh, inconsistent disciplining, neglectful child rearing
genetic and physiological factors
oppositional defiant disorder factors: neurobiological markers (reduced basal cortisol reactivity, abnormality in PFC and amygdala
6 months
how long does oppositional defiant disorder need to last for?
oppositional defiant disorder
child often loses temper, angry and resentful, argues with authority figures, refuses to comply with rules, deliberately annoys others, blames others, spiteful or vindictive behaviors at least twice
angry/irritable mood
criteria for oppositional defiant disorder: often loses temper, often touchy or easily annoyed, angry or resentful
argumentative/defiant behavior
criteria for oppositional defiant disorder: argues with authority, children, or adolescents, denies or refuses to comply with requests or rules, deliberately annoys others, blames others for behavior
vindications
criteria for oppositional defiant disorder: has been spiteful at least twice within the past 6 months
1st line therapy
adjunct pharmacotherapy (aggression especially)
what is the treatment for oppositional defiant disorder?
atypical antipsychotics and mood stabilizers
what pharmacotherapy can be used as an adjunct therapy for aggressive children with oppositional defiant disorder?
SSRI
what pharmacotherapy can be used as an adjunct therapy for aggressive children with anxiety or sadness
intermittent expolosive disorder
impulsive aggressive outbursts that are anger based with NO PRODROMAL PERIOD
late childhood/adolescence
what is the most common age onset for intermittent explosive disorder?
males
what gender is more common with intermittent explosive disoroder?
intermittent explosive disorder
verbal aggression (temper tantrums, verbal arguments, fights) or physical aggression towards property, animals, of other individuals
occurring twice weekly for 3 months
what is the minimal duration for aggression for intermittent explosive disorder?
intermittent explosive disorder
verbal aggression and physical aggression that results in physical injury against animals or other individuals within a 12 month period
intermittent explosive disorder
recurrent aggressive outbursts are NOT premeditated (they are impulsive or anger based, in which they cannot control their behavior)
6 years old or older
what age must you be to be diagnosed with intermittent explosive disorder?
therapy
adjunct pharmacotherapy
what is the treatment for intermittent explosive disorder?
conduct disorder
an enduring set of behaviors in a child/adolescent that evolves over time, characterized by AGGRESSION and VIOLATION of the rights of others
physical aggression, destruction of property, acts of deceit/theft, and frequent violation of age appropriate rules
what are the 4 categories for conduct disorder?
pre mediated, not pre mediated
conduct disorder is (pre mediated, not pre meditated)
intermittent explosive disorder is (pre mediated, not pre meditated)
males
what gender is conduct disorder more common in?
ODD
what is a common precursor to conduct disorder?
males: 10-12 years
females: 14-16 years
what is the average age of onset for conduct disorder in males? females?
conduct disorder
expressing overt aggressive behavior, frequently misperceive the intentions of others as more hostile and threatening
overt behavior
openly demonstrating your aggression (walking up and punching someone in the face)
covert behavior
doing something sneakily behind someones back
conduct disorder
substance misuse, suicidal ideation, suicide attempts, and completed suicide occur at a higher than expected rate in this disorder
conduct disorder
negative emotionality, poor self control, poor frustration tolerance, irritability, temper outbursts, suspiciousness, insensitivity to punishment, thrill seeking, recklessness
aggression to people or animals
conduct disorder criteria: bullies, threatens other, physical fights, used weapons, physically cruel to people or animals, stolen while confronting a victim, has forced someone into sexual activity
3 or more in the past 12 months, 1 or more in the past 6 months
how many symptoms and how long do symptoms have to occur in conduct disorder?
destruction of property
conduct disorder criteria: fire setting with intention of causing serious damage
deceitfulness or theft
conduct disorder criteria: breaking into someone else's house, cars, lies to obtain goods, stolen items of nontrivial value
serious violations of rules
conduct disorder criteria: stays out at night despite parental prohibitions, run away from home twice, of once without returning home for a lengthy period, often truant from school
below 18 years old
if above 18, be concerned about antisocial personality disorder
what is the age LIMIT for conduct disorder?
what disorder is it if they are above this age?
multimodality recommended: pharmacotherapy and behavioral intervention
what is the treatment for conduct disorder?
atypical antipsychotics (decrease agitation and aggression)
mood stabilizers, SSRIs can also be used
what is the chosen pharmacotherapy for conduct disorder?
ADHD
a pattern of diminished sustained attention and higher levels of impulsivity
dopamine
what neurotransmitter is involved the most in ADHD?
premature, maternal infections during pregnancy, perinatal birth injury, infection
what are some developmental factors that might cause ADHD?
chronic abuse, maltreatment, and neglect
what are some psychosocial factors for ADHD?
1st relatives, siblings with ADHD, low birth weight, tobacco use during pregnancy
what are some risk factors for ADHD?
males
what gender is ADHD more prevalent in?
false, needs to be in at least 2 different settings
true or false: impulsivity or inattention only at home is enough to diagnose someone with ADHD
ADHD
short attention span, high levels of distractibility
hyperactivity symptoms
excessive motor activity, excessive fidgeting, tapping, talkativeness
inattention symptoms
short attention span, wandering off task, lacking persistance, difficulty sustaining focus/poor concentration
impulsivity symptoms
hasty actions that occur in the moments without forethought and have high potential for harm to the individual, lack of organization
ADHD
low frustration tolerance, irritability, mood swings, academic/work performance impaired, cognitive problems, difficulty with memory
easily upset by noise, light, temperature; active in crib, sleeps little, cries alot
what are some symptoms of ADHD in infants?
attacks test rapidly but only answers the 1st few questions, unable to sit still, blurts out responses to questions, explosive, irritable
what are some symptoms of ADHD in chikldren?
true
true or false: there are brain wave changes (EEG irregularity) in those with ADHD
true
may see decreased hyperactivity, but remain impulsive and accident prone
true or false: children with ADHD can have symptoms wane into adulthood
6 or more inattention AND/OR hyperactivity/impulsivity symptoms that have lasted for 6 months or more
what is the symptom criteria for ADHD?
inattentive ADHD criteria
fails to give close attention to details, makes careless mistakes in school/work, difficulty staining attention, does not seem to listen when spoken to directly, does not follow through on instruction, difficulty organizating
inattentive ADHD criteria
avoids, dislikes or is reluctant to engage in tasks that require sustained mental effort, loses things necessary for tasks, often easily distracted, often forgetful in daily activities
impulsive/hyperactive ADHD criteria
fidgets with or taps hands, squirms in seat, leaves seat in classroom, runs about, climbs excessively, difficulty playing or engaging in leisure activities, often "on the go" or driven by a motor
impulsive/hyperactive ADHD criteria
talks excessively, blurts out answers before questions have been completed, often has difficulty waiting for their turn, often interrupts or intrudes on others
true
true or false: you can have predominantly inattentive ADHD and not impulsive ADHD
pharmacotherapy, CNS stimulants are the 1st line
behavior modification programs are other interventions
what is the 1st line treatment for ADHD?
adderall, focalin, ritalin, concerta, methylin, dexerdrine, procentra, vyvanase
what are the 1st line stimulant medications for ADHD treatment?
tachycardia, heart palpitations, increased BP, decreased appetite, GI upset, headache, ansomnia, seizures
what are some adverse effects of stimulants?
false
true or false: stimulants do not have a potential for addiction and future substance abuse
monitor height and weight, they are ADRs
what should we monitor in ADHD patients who are on stimulants?
non stimulants (kapvay, intuiv, straterra)
what is the 2nd line treatment for ADHD?
wellbutrin (bupropion), an atypical antidepressant
what is the 3rd line for ADHD treatment?
NE-DA reuptake inhibitor (leaving them in the synapse)
what is the MOA for wellbutrin?
wellbutrin
what med used for ADHD lowers the seizure threshold so it has the potential to cause seizures
as young as 7
we can use wellbutrin in ADHD patients as young as what age?
wellbutrin
we can use what med in patients with ADHD and concurrent depression symptoms?
before 12 years old
remission of ADHD is unlikely before what age?
conduct disorder
those with ADHD are at an increased risk for what other mental disorder if symptoms persist into adolescence?
higher rates of comorbid psychiatric disorders and more problems with behavior
socially dysfunctional children + ADHD = what?
between 12-20
what age does remission commonly occur in ADHD?
combined ADHD, stimulants
a 6 year old male patient presents with his parents for a yearly check up. his parents have some concerns about behavior at school and at home. mother states that "he seems to struggle with concentrating on his schoolwork" she describes the patient as unorganized, forgetful, and says he gets a lot of questions wrong on his homework because he rushes through it. it is hard for him to sit still. this happens as well wit household chores. patient's mother states that he has too much energy! he is tapping his foot on the table and ripping at the exam table paper at the visit. what is the most likely diagnosis? what is the 1st line treatment?
conduct disorder, multimodality treatment, therapy, pharmacotherapy (ANTIPSYCHOTICS).
mood stabilizers and SSRIs can also be used.
a 13 year old boy presents with his foster mother who is concerned for behavioral issues. patient's foster mother states that his attitude and actions are getting worse. patient was expelled from his school for fighting and bullying this past well. it has been happening for a year. she had to give away the family dog because she was scared for the dog's safety. she says that he bets up his brother and is consistently disrespectful to the foster mother. he also breaks into the neighbors house for stealing. what is the diagnosis and treatment?
autism spectrum disorder (ASD)
disorder that is characterized by impairment in social interaction and social communication, restricted repetitive patterns of behavior, interests, and activities
level of severity and presence/absence of associated conditions
what are the specifiers of ASD?
genetic basis
what is the etiology of ASD in most cases?
no
is there any evidence to support assoication with vaccines?
siblings of a child with autism
what are the risk factors for an increased rate of autism?
genes, imbalances in NTs, prenatal toxin exposures, prenatal maternal infections, advanced parental age
what are some etiology risk factors for ASD?
45-60%
what percentage of ASD is due to intellectual disability?
11-39%
what percentage of ASD is associated with seizures?
PKU, fetal alcohol syndrome, fragile x syndrome
what are some miscellaneous conditions for ASD?
boys
ASD is more frequent in what gender?
ASD
early communicative behaviors, trouble tolerating change, possible seizures, self injury
tuberous sclerosis
rare, multi-system genetic disorder that causes the growth of benign tumors in various organs, including the brain, kidneys, heart, liver, eyes, lungs, and skin. Symptoms may include seizures, intellectual disability, and developmental delay.
12-24 months
when is ASD most commonly recognized?
impaired social communication
what is the hallmark for ASD?
ASD
delayed language development, regression of skills, deficits in emotion/social reprocity, decreased/lack of joint attention, impaired ability to interpret nonverbal behaviors (eye contact, gestures), fail to develop peer relationships