Adipose Tissue

Adipocytes

fat-storing cells

Adipose Tissue

compromised by adipocytes

White Adipose Tissue and Brown Adipose Tissue

2 Major Types of Adipose Tissue

White Adipose Tissue

more common type specialized for fat storage, consists of cells each containing one large cytoplasmic droplet of whitish-yellow fat

Brown Adipose Tissue

contains cells with multiple lipid droplets interspersed among abundant mitochondria, which helps give this tissue a darker appearance

White Adipose Tissue

Specialized for relatively long-term energy storage

Unilocular

what white adipocytes are called due to its single large droplet of triglycerides

white adipose tissue

what adipose tissue is this

1. Dietary fats brought to the cells via the circulation as chylomicrons

2. Lipids synthesized in the liver and transported in blood with very low-density lipoproteins (VLDLs)

3. Free fatty acids and glycerol synthesized by the adipocytes

White adipocytes can store triglycerides derived from three sources:

Lipoprotein lipase

an enzyme that hydrolyzes chylomicrons and VLDLs at the luminal surfaces of blood capillaries

Insulin

stimulates glucose uptake by adipocytes and accelerates its conversion into triglycerides, and the production of lipoprotein lipase

Leptin

the 16-kDa polypeptide hormone that is produced by hormonal activity of white adipocytes

Preadipocytes

first developed in adipose development

White Adipocytes, Beige Adipocytes, and Brown Adipocytes

Preadipocytes then develop into three namely:

2%-5%

Brown adipose tissue constitutes of the newborn body weight, located mainly in the back, neck, and shoulders

Multilocular

what brown adipocytes are called because of many small lipid inclusions it has

cytochrome

The color of brown adipose tissue is due to the very abundant mitochondria that contains pigment

brown adipose tissue

what adipose tissue is this

Thermogenesis

the main function of these multilocular adipose cells (brown adipocytes)

Thermogenin

transmembrane protein of brown adipocyte’s mitochondrial membrane

earlier

Brown adipocytes emerge than white fat during fetal development

increases

The number of brown adipocytes during cold adaptation