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What is the most important thing to know about IgG and IgM in viral infections?
IgM = ACUTE/Current infection
IgG = PAST infection / Immunity
What is EBV?
Epstein-Barr Virus
Which is the most important infection that EBV causes?
Infectious Mononucleosis (MONO)
Which infection is associated with ATYPICAL LYMPHS and heterophile antibodies?
MONO
Which 2 tests detect for HETEROPHILE antibodies of MONO?
Monospot / Paul-Bunnell
IN EBV/MONO what does the presence of Viral Capsid Antigen (VCA) IgM indicate?
ACUTE/Active infection
In EBV/MONO what does the presence of VCA-IgG indicate?
Acute or PAST MONO infection
What are Heterophile Antibodies?
Antibodies produced against one antigen that CROSS REACT with antigens from ANOTHER SPECIES
Which MONO antibody test involves BEEF absorbing Mono heterophile antibodies?
Davidsohn Differential