what effects actin?
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5 Terms
how does latrunculin effect actin filament formation
prevents actin polymerisation by binding to actin subunits
how does cytochalasin B effect actin filament formation
fungal products that prevent actin polymerisation by binding to plus end of actin filaments
how does phalloidin effect actin filament formation
bind tightly along all sides of actin filament stabilizing them against depolymerisation
how does thymosin affect actin polymerization
binds to actin monomers making polymerization much less favourable- the monomers are in a locked state where they can’t associate with the plus/ minus ends of filament
how does profilin affect actin polymerization
binds to face of actin opposite ATP binding site blocking side that normally associates the monomer with the minus end. Monomer only joins plus end instead promoting growth