Substitution Reactions

SN2 reactions are one or two steps

One step

What is the rate law for SN2 reactions?

Rate = k[electrophile][nucleophile]

The product of SN2 reactions displays an ______

Inversion of configuration

SN1 reactions are one or two steps?

Two steps

What is the rate law for SN1 reactions?

Rate = k[electrophile]

The product of SN1 reactions displays an ______

Racemic mixture

Which substitution reactions partakes in a carbocation rearrangment

SN1

Which nucleophile is required for SN2 reactions?

Strong nucleophile

Which electrophiles are required for SN2 reactions?

CH3>1°>2°

CH3 is most reactive and then 1° and then 2°

Which solvent is required for SN2

Polar aprotic

What type of nucleophile is required for SN1 reactions?

Weak is ok

Which electrophiles are needed for SN1 reactions?

3°>2°

3° is most reactive and then 2°

Which solvent is needed for SN1 reactions?

Polar protic

Both SN1 and SN2 reactions require good leaving groups, what are the rankings for good nucleophiles?

I>Br>Cl>F

For substitution, the carbon with the leaving group must be an ______

sp3 carbon

What is the difference between polar protic and polar aprotic solvents?

Polar protic solvent can hydrogen bond

Polar aprotic solvents cannot