Toxidromes and Antidotes

Sympathomimetic symptoms

tachycardia, hypertension, agitation, flushing, diaphoresis, mydriasis, active bowel sounds, seizures

Sympathomimetic drugs

amphetamines, bath salts, caffeine, cocaine, alc/benzo withdrawal

Antimuscarinic Symptoms

tachycardia, hypertension, delirium/mumbled speech, flushing, anhidrosis, quiet bowel sounds, urinary retention, seizures

Antimuscarinic drugs

antihistamine, antipsychotics, tricyclic antidepressants, weed, benztropine, cyclobenzaprine

Muscarinic drugs

organophosphates, carbamates, nerve agents, pilocarpine, muscarine mushrooms

Muscarinic symptoms

diarrhea, urination, miosis, bradycardia, bronchorrhea, emesis, lacrimation, salivation

Opioid drugs

codeine, fentanyl, heroine, morphine, tramadol

Opioid symptoms

CNS depression, respiratory depression, miosis, ileus, bradycardia, hypothermia

Serotonergic drugs

SSRI, SNRI, stimulants, LSD, psilocybin

Serotonergic symptoms

tachycardia, labile bp, diaphoresis, increased bowel sounds, clonus, hyperreflexia, rigidity, tremor

Sedative hypnotic drugs

Ethanol, Carisoprodol, GHB, chloral hydrate

Sedative-hypnotic symtpoms

CNS depression, respiratory depression, variable HR

Opioid Withdrawal Symptoms

N/V, yawning, piloerection, rhinitis