60 - SAM

What are the most common breeds predisposed to canine lymphoma?

Cocker Spaniels

What is the most common form of canine lymphoma and what is its typical presentation?

Diffuse large cell lymphoma

How is canine lymphoma most commonly diagnosed cytologically?

Greater than 50% lymphoblasts in a lymph node aspirate or a monomorphic population of abnormal small or intermediate lymphocytes

What additional diagnostics can help diagnose lymphoma when cytology is inconclusive?

Biopsy

What are the primary staging diagnostics for canine lymphoma?

CBC (commonly anemia and thrombocytopenia)

What is the standard first-line treatment for canine lymphoma and what drugs make up the CHOP-like protocol?

Systemic chemotherapy

What is the typical canine CHOP-like treatment schedule and response rate for B-cell diffuse large cell lymphoma?

16 doses over approximately 6 months

How is response to lymphoma chemotherapy classified?

Complete response = resolution of detectable disease

When is radiation therapy used for canine lymphoma?

Generally as an adjunct to chemotherapy for localized symptomatic disease such as CNS

Which breeds are predisposed to canine osteosarcoma?

Scottish Deerhounds

What is the typical signalment and primary location of canine osteosarcoma?

Middle-aged to older large and giant breed dogs

What are the most common anatomical locations of appendicular osteosarcoma?

Distal radius is most common

What is the typical metastatic behavior of osteosarcoma?

Highly malignant high-grade tumor

What are common clinical signs of osteosarcoma?

Lameness

What are characteristic radiographic findings of osteosarcoma?

Aggressive bone disease

What is the minimum staging database for canine osteosarcoma?

Thoracic radiographs

What is the standard treatment for appendicular osteosarcoma and why is chemotherapy recommended afterward?

Amputation removes the primary tumor

What are the median survival times for canine osteosarcoma with amputation alone versus amputation and chemotherapy?

Amputation alone = 4-6 months

Which breeds are predisposed to canine hemangiosarcoma?

Golden Retrievers

What are the most common visceral locations and clinical presentations of canine hemangiosarcoma?

Spleen